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作 者:Aspasia Toli Asli Perente Georgios Labiris
机构地区:[1]Department of Ophthalmology,University Hospital of Alexandroupolis,Alexandroupolis 68100,Greece
出 处:《World Journal of Methodology》2021年第5期263-277,共15页世界方法学杂志
摘 要:BACKGROUND Red reflex test(RRT)is a simple,non-invasive method that can be performed easily by pediatricians during the clinical examination in neonatal period,infancy and childhood.Abnormal reflexes can lead to prompt diagnosis of several ocular disorders,with potentially severe consequences on patient’s vision,cognitive function and even life.AIM To underline the contribution of pediatricians to early detection of vision and life threatening diseases by using RRT effectively.METHODS For the present systematic review,PubMed searches were performed using the key words“red reflex and newborn”;“red reflex and neonate”;“red reflex and complications”;“red reflex and necessity”;“red reflex and retinoblastoma”;“red reflex and congenital cataract”;“red reflex and glaucoma”;“red reflex and prematurity”;“red reflex and leukocoria”;“red reflex and blindness”;“red reflex sensitivity and specificity”;“red reflex and differential diagnosis”;“red reflex and guidelines”.The relevant articles were selected without language restrictions.When a full-text publication was not available,their English abstracts were used.In some cases,studies from the reference lists of the selected articles provided useful information.The research took place in September 2020,in the Ophthalmology Department of University Hospital of Alexandroupolis.RESULTS A total of 45 articles were selected according to the used key words.After reviewing data from these articles,it is supported that red reflex remains an effective tool of undeniable importance for early detection of severe eye conditions,such as cataract,retinoblastoma,retinopathy of prematurity and glaucoma.Although literature reports some limitations of RRT,including a notable percentage of false positive tests,the inability to detect small,peripheral retinoblastomas and the lower sensitivity for posterior segment pathology,it is widely accepted that the benefits from the regular evaluation of the test on public health are significant.Therefor
关 键 词:Red eye reflex LEUKOCORIA Visual screening NEWBORN Prevention Pediatric examination
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