Impact of COVID-19 on liver  

作　　者：Yu-Jang Su Chen-Wang Chang Ming-Jen Chen Yen-Chun Lai 

机构地区：[1]Department of Emergency Medicine,MacKay Memorial Hospital,Taipei City 10449,Taiwan [2]Poison Center,Department of Emergency Medicine,MacKay Memorial Hospital,Taipei City 10449,Taiwan [3]Yuanpei University of Medical Technology,HsinChu 30015,Taiwan [4]MacKay Junior College of Medicine,Nursing and Management,Taipei City 25245,Taiwan [5]Department of Medicine,MacKay Medical College,New Taipei City 25245,Taiwan [6]Division of Gastroenterology and Hepatology,Department of Internal Medicine,MacKay Memorial Hospital,Taipei City 10449,Taiwan [7]Department of Anesthesiology,Taipei Medical University Hospital,Taipei City 110301,Taiwan [8]Heroic Faith Medical Science Company,Taipei 11493,Taiwan

出　　处：《World Journal of Clinical Cases》2021年第27期7998-8007,共10页世界临床病例杂志

摘　　要：The incidence of liver injury after coronavirus disease 2019(COVID-19)infection ranged from 15%-53%.The mechanism includes direct viral cytopathic effect,cytokinesis,and treatment drug-induced liver injury.The symptoms include nausea,vomiting,diarrhea,and loss of appetite.The laboratory results include increased liver enzyme levels,decreased monocyte count,and longer prothrombin time.The most common imaging findings are hepatomegaly on ultrasound,ground-glass opacity on chest computed tomography(CT),and liver hypodensity and pericholecystic fat stranding on abdominal CT.Patients may also have different presentations and poor outcomes of different liver diseases concomitant with COVID-19 infection.Liver function test(LFT)results should be monitored,and all factors known to cause or predispose liver injury should be investigated while managing the patients.The risks of transfer to an intensive care unit,need for mechanical ventilator support,and acute kidney injury is higher in COVID-19 patients with than without abnormal LFTs.Increased mortality and length of hospital stay are both observed.

关 键 词：COVID-19 Fatty liver Liver cirrhosis HEPATITIS HYPOALBUMINEMIA Hepatic injury 

分 类 号：R563.1[医药卫生—呼吸系统] R575[医药卫生—内科学]