Madelung’s disease with alcoholic liver disease and acute kidney injury: A case report  

作　　者：Ling Wu Ting Jiang Yan Zhang An-Qi Tang Li-Hua Wu Yu Liu Ming-Quan Li Liang-Bin Zhao 

机构地区：[1]Department of Nephrology,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,Sichuan Province,China [2]Department of Ultrasound,Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,Sichuan Province,China

出　　处：《World Journal of Clinical Cases》2021年第27期8199-8206,共8页世界临床病例杂志

基　　金：Supported by the National Natural Science Foundation of China,No.81973831;the Sichuan Provincial Department of Finance,Sichuan Provincial Department of Labor and Social Security(2020)No.201 Traditional Chinese Medicine Inheritance and Innovation Ten Thousands of Talents Project-Ye Chuanhui Studio.

摘　　要：BACKGROUND Madelung’s disease(MD)is a rare disorder of lipid metabolism,characterized by the growth of unencapsulated masses of adipose tissue symmetrically deposited around the neck,shoulders,or other sites around the body.Its pathological mechanism is not yet known.One of the most common comorbidities in MD patients is liver disease,especially chronic alcoholic liver disease(CALD);however,no reports exist of acute kidney injury(AKI)with MD.CASE SUMMARY We report a 60-year-old man who presented with complaint of edema in the lower limbs that had persisted for 3 d.Physical examination showed subcutaneous masses around the neck,and history-taking revealed the masses to have been present for 2 years and long-term heavy drinking.Considering the clinical symptoms,along with various laboratory test results and imaging characteristics,a diagnosis was made of MD with acute exacerbation of CALD and AKI.The patient was treated with liver function protection and traditional Chinese medicine,without surgical intervention.He was advised to quit drinking.After 10 d,the edema had subsided,renal function indicators returned to normal,liver function significantly improved,and size of subcutaneous masses remained stable.CONCLUSION In MD,concomitant liver or kidney complications are possible and monitoring of liver and kidney functions can be beneficial.

关 键 词：Madelung’s disease Multiple symmetric lipomatosis DRINKING Alcoholic liver disease Acute kidney injury Case report 

分 类 号：R589.2[医药卫生—内分泌] R575[医药卫生—内科学] R692[医药卫生—临床医学]