CT定量检测侧脑室容量动态变化与围生期缺氧性脑损伤预后相关性研究  

Study on the Correlation between the Dynamic Changes of Lateral Ventricular Volume Measured by CT and the Prognosis of Perinatal Hypoxic Brain Injury

作　　者：肖波涛[1] XIAO Bo-tao(Department of Radiology,Maternal and Child Health Hospital of Huanggang,Huanggang 438000,Hubei Province,China)

机构地区：[1]湖北省黄冈市妇幼保健院放射科,湖北黄冈438000

出　　处：《罕少疾病杂志》2021年第5期5-7,共3页Journal of Rare and Uncommon Diseases

基　　金：黄冈市科技局2020年科技项目(XQYF2020000034)。

摘　　要：目的探讨CT定量检测侧脑室容量动态变化与围生期缺氧性脑损伤(HIE)预后的相关性。方法回顾性选择2018年10月至2019年12月于我院CT室检查的81例HIE新生儿,所有患儿均于出生后2d、4周、3个月进行CT脑室容量检查,测量脑室哈氏值、前角指数、脑室指数和第三脑室宽度。根据有无神经系统后遗症将患儿分为预后良好组和预后不良组,观察组间脑室哈氏值、前角指数、脑室指数和第三脑室宽度的变化和差异,分析脑室哈氏值、前角指数、脑室指数和第三脑室宽度对新生儿预后的预测价值。结果HIE患儿预后不良率37.04%,预后不良组HIE病情程度较预后良好组重、合并症较预后良好组多,哈氏值、脑室指数、第三脑室宽度随HIE病情程度加重而增加(P<0.05),前角指数则逐渐降低(P<0.05)。预后不良组患儿出生后2d哈氏值、脑室指数、第三脑室宽低于预后良好组(P<0.05),前角指数大于预后良好组(P<0.05),治疗后3个月后哈氏值、脑室指数、第三脑室宽度大于预后良好组(P<0.05)。出生后2d哈氏值、脑室指数、第三脑室宽度对HIE预后预测具有较高效能,AUC分别为0.872、0.869、0.808。结论CT定量检测侧脑室容量指标对HIE病情判断和预后预测均具有较高价值。Objective To investigate the correlation between the dynamic changes of lateral ventricular volume measured by CT and the prognosis of perinatal hypoxic brain injury(HIE).Methods A retrospective study was conducted on 81 HIE neonates examined in the CT room from October 2018 to December 2019.All neonates were examined by CT ventricular volume at 2 days,4 weeks,and 3 months after birth.The ventricular Harrington's value,anterior horn index,ventricular index,and third ventricular width were measured.The children were divided into the good prognosis group and the poor prognosis group according to the presence or absence of neurological sequelae.The changes and differences of ventricular Harrington's value,anterior angle index,ventricular index,and third ventricular width were observed.The predictive value of ventricular Harrington's value,anterior angle index,ventricular index,and third ventricular width for neonatal prognosis was analyzed.Results The prognosis rate of children with HIE was 37.04%.The degree of HIE in the poor prognosis group was higher than that in the prognosis group.The complication was better than the prognosis group.The Hastelloy value,ventricular index,and third ventricle width increased with the severity of HIE.The increase was(P<0.05),and the anterior angle index was gradually decreased(P<0.05).In the poor prognosis group,the Had value,ventricular index,and third ventricle width were lower than the prognosis group(P<0.05),and the anterior angle index was greater than the prognosis group(P<0.05).The mean value,ventricular index,and third ventricle width were larger than those with a good prognosis(P<0.05).The 2d-month Had value,ventricular index,and third ventricle width were more effective in predicting the prognosis of HIE,with AUC of 0.872,0.869,and 0.808,respectively.Conclusion Quantitative measurement of lateral ventricular volume by CT is of great value in judging the condition and predicting the prognosis of HIE.

关 键 词：CT 脑室容量动态变化 围生期缺氧性脑损伤 预后 

分 类 号：R445.3[医药卫生—影像医学与核医学] R814.42[医药卫生—诊断学]