大矩阵超高分辨CT结合iDose^(4)算法筛查新型冠状病毒肺炎技术探讨  

Technology Discussion of Ultra High Resolution CT and iDose^(4) Algorithm for Screening COVID-19

作　　者：郭鹭鑫 康江河[1] 蔡小萍 王金岸[1] GUO Lu-xin;KANG Jiang-he;CAI Xiao-ping;WANG Jin-an(Department of Imaging,Zhongshan Hospital Affiliated to Xiamen University,Xiamen 361004,Fujian Province,China)

机构地区：[1]厦门大学附属中山医院影像科,福建厦门361004

出　　处：《罕少疾病杂志》2021年第5期21-23,30,共4页Journal of Rare and Uncommon Diseases

摘　　要：目的评价超高分辨CT(UHRCT)结合iDose^(4)迭代算法的图像质量,探讨其在新型冠状病毒肺炎(COVID-19)诊断中的应用价值。方法对行Philips Ingenuity CT扫描的25例疑似COVID-19患者原始CT图像,分512矩阵组及1024矩阵组,采取传统滤过反投影法(FBP)及iDose^(4)-1、iDose^(4)-3、iDose^(4)-5、iDose^(4)-7进行回顾性重建,测量不同重建图像肺窗同一层面的CT值、噪声(SD)、信噪比(SNR);由3名影像学高级职称医师以5分制对图像质量及显示肺小叶结构进行主观评分。所有数值进行SPSS统计学分析。结果iDose^(4)-1、iDose^(4)-3、iDose^(4)-5、iDose^(4)-7的SNR均高于FBP,噪声低于FBP,差异有统计学意义(P<0.05),各组图像的CT值差异无统计学意义(P>0.05)。随着iDose^(4)级别的增高,SD值下降,SNR值升高。同一迭代等级,1024矩阵组SD值高于512矩阵组,SNR值低于512矩阵组,差异具有统计学意义(P<0.05)。两两比较显示,1024矩阵组iDose^(4)-5、iDose^(4)-7与512矩阵组iDose^(4)-3的SD、CNR差异无统计学意义(P>0.05)。FBP、不同级别迭代重建图像主观评分差异有统计学意义(P<0.05)。各组间两两比较,同一矩阵条件下iDose^(4)-3、iDose^(4)-5的主观评分值差异无统计学意义(P>0.05),且1024矩阵iDose^(4)-5主观评分优于其它组,差异有统计学意义(P<0.05)。结论1024矩阵超高分辨CT结合iDose^(4)-5重建可以更清楚显示肺小叶结构、磨玻璃病灶及细或末梢支气管扩张,有利于精准评估COVID-19病变的累及范围及程度。Objective To evaluate the image quality and diagnostic value of ultra high resolution CT(UHRCT)combined with iDose^(4) iterative algorithm in novel coronavirus(COVID-2019)pneumonia.Methods Twenty five cases of suspected(Corona Virus Disease 2019,COVID-2019)patients'original CT images were divided into 512 matrix group and 1024 matrix group Traditional filter back projection(FBP)and iDose^(4)-1,iDose^(4)-3,iDose^(4)-5,iDose^(4)-7 iterative reconstruction were used for retrospective reconstruction.CT values,noise(SD)and signal-to-noise ratio(SNR)at the same level of lung window of different reconstructed images were measured.The image quality were evaluated by 3 experienced radiologists respectively using 5-point system.Resuts The SNR values of iDose^(4)-1,iDose^(4)-3,iDose^(4)-5,iDose^(4)-7 were higher than those of FBP,and the noise was lower than that of FBP.The differences were statistically significant(P<0.05).There was no statistically significant difference in CT value of each group(P>0.05).With theincrease of iteration level,SD decreased and SNR increased.At the same iteration level,SD value of 1024 matrix group was higher than 512 matrix group,SNR value was lower than 512 matrix group,the difference was statistically significant(P<0.05).There was no significant difference in SD and CNR between iDose^(4)-5,iDose^(4)-7 of 1024 matrix and iDose^(4)-3 of 512 matrix(P>0.05).There were significant differences in subjective scores of FBP and different iterative reconstructionimages(P<0.05).There was no significant difference between the subjective scores of iDose^(4)-3 and iDose^(4)-5 in the same matrix(P>0.05),and the subjective scores of idose5 in matrix 1024 were better than those in other groups(P<0.05).Conclusion Ultra high resolution CT of 1024 matrix combined with iDose^(4)-5 reconstruction can clearly show more detail structures of pulmonary lobules,ground glass lesions and bronchiectasis,It is helpful to evaluate the extent of COVID-19.

关 键 词：超高分辨CT 1024矩阵 迭代重建 新型冠状病毒肺炎 

分 类 号：R445.3[医药卫生—影像医学与核医学] R563.1[医药卫生—诊断学]