A2DS2评分联合中性粒细胞与淋巴细胞比值对卒中相关性肺炎的预测价值  

Value of A2DS2 score combined with neutrophil to lymphocyte ratio in predicting stroke-associated pneumonia

作　　者：宋雅妹[1] 邢佳[1] 张谨超[2] 崔朝勃[1] 张菊香[1] 王晶[1] Song Yamei;Xing Jia;Zhang Jinchao;Cui Chaobo;Zhang Juxiang;Wang Jing(Department of Respiratory and critical Care Medicine,Harrison International Peace Hospital,Hengshui 053000,China)

机构地区：[1]哈励逊国际和平医院呼吸与危重症科,河北衡水053000 [2]哈励逊国际和平医院重症医学科,河北衡水053000

出　　处：《临床内科杂志》2021年第8期526-528,共3页Journal of Clinical Internal Medicine

基　　金：河北省医学科学研究重点课题计划(2018014014Z)。

摘　　要：目的探讨A2DS2评分联合中性粒细胞(NEUT)与淋巴细胞(LY)比值(NLR)对卒中相关性肺炎(SAP)的预测价值。方法根据是否合并SAP将226例脑卒中患者分为SAP组124例和非SAP组102例,比较两组患者的临床资料。采用多元logistic回归分析评估SAP的危险因素。采用受试者工作特征(ROC)曲线评估A2DS2评分、NLR对SAP的预测价值。结果SAP组患者年龄、有吸烟史、心房颤动病史、吞咽困难及缺血性脑卒中患者比例、美国国立卫生研究院卒中量表(NIHSS)评分、A2DS2评分、WBC计数、NEUT计数及NLR均高于非SAP组(P<0.05),LY计数低于非SAP组(P<0.05)。多元logistic回归分析结果显示,A2DS2评分和NLR均是SAP的独立危险因素(P<0.05)。ROC曲线分析结果显示,A2DS2评分联合NLR预测SAP的ROC曲线下面积(AUC)高于单一指标(P<0.05)。结论A2DS2评分联合NLR对SAP具有良好的预测价值。Objective To explore the value of A2DS2 score combined with neutrophil to lymphocyte ratio(NLR)in predicting stroke-associated pneumonia(SAP).Methods According to combined with SAP or not,226 patients with stroke were divided into SAP group(124 cases)and non-SAP group(102 cases),clinical data between the two groups were compared.Multivariate logistic regression analysis was used to assess the risk factors of SAP.Receiver operating characteristic(ROC)curve was used to evaluate the predictive value of A2DS2 score and NLR for SAP.Results Age,ratios of patients with smoking history,disease history of atrial fibrillation,dysphagia,ischemic stroke,National Institutes of Health Stroke Scale(NIHSS)score,A2DS2 score,WBC count,NEUT count and NLR in SAP group were all higher than those in non-SAP group(P<0.05),while LY count was lower than that in non-SAP group(P<0.05).Multivariate logistic regression analysis showed that both A2DS2 score and NLR were the independent risk factors for SAP(P<0.05).ROC curve analysis showed that area under ROC curve(AUC)of A2DS2 score combined with NLR predicted SAP was higher than a single index(P<0.05).Conclusion A2DS2 score combined with NLR has a good predictive value for SAP.

关 键 词：卒中相关性肺炎 A2DS2评分 中性粒细胞与淋巴细胞比值 

分 类 号：R563.1[医药卫生—呼吸系统]