Recognition of glycine by cucurbit[5]uril and cucurbit[6]uril:A comparative study of exo-and endo-binding  

作　　者：Peihui Shan Ruilian Lin Ming Liu Zhu Tao Xin Xiao Jingxin Liu 

机构地区：[1]Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province.Guizhou University,Guiyang 550025,China [2]College of Chemistry and Chemical Engineering,Anhui University of Technology,Maanshan 243002,China

出　　处：《Chinese Chemical Letters》2021年第7期2301-2304,共4页中国化学快报（英文版）

基　　金：supported by the National Natural Science Foundation of China(No.21861011);the Innovation Program for High-level Talents of Guizhou Province(No.2016-5657);the Major Program for Creative Research Groups of Guizhou Provincial Education Department(2017-028);the Science and Technology Fund of Guizhou Province(No.2018-5781);the Natural Science Foundation of Anhui Province of China(Nos.1808085MB43,2008085MB36)。

摘　　要：Recognition features of glycine(Gly)with cucurbit[5]uril(Q[5])and cucurbit[6]uril(Q[6])both in aqueous solution and solid state were investigated by 1 H NMR spectroscopy and X-ray crystallography.1 H NMR data indicate that the Gly is located outside of the portals of the Q[5],exhibiting exo binding with the Q[5].In the case of the Q[6],the Gly shows endo binding or a dual binding mode(endo and exo binding)with the host,which depends on the amount of the host in the aqueous solution.X-ray crystallography clearly display that the Gly forms 2:1 exclusion complex with the Q[5],and 2:1 inclusion complex with the Q[6].Interestingly,hydrogen bondings between the encapsulated Gly molecules in the Q[6]were observed.

关 键 词：CUCURBITURIL endo-Binding exo-Binding Selective recognition Supramolecular assembly 

分 类 号：O629.71[理学—有机化学]