Microbes as a production host to produce natural active compounds from mushrooms:biosynthetic pathway elucidation and metabolic engineering  

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作  者:YANG Li-Yang GONG Qiang GUO Jian-Quan LI Gui-Lan 

机构地区:[1]School of Basic Medical Sciences,Shanxi University of Chinese Medicine,Jinzhong 030619,China [2]School of Public Health,Shanxi Medical University,Taiyuan 030001,China

出  处:《Chinese Journal of Natural Medicines》2021年第8期580-590,共11页中国天然药物(英文版)

基  金:supported by the Key Research and Development Program for Science and Technology of Jinzhong(No.Y191021);the Basic Research Project of Shanxi University of Traditional Chinese Medicine(No.2020PY-JC(Y)-05);the Research Project Supported by Shanxi Scholarship Council of China(No.2020-132)。

摘  要:Mushrooms are abundant in bioactive natural compounds.Due to strict growth conditions and long fermentation-time,microbe as a production host is an alternative and sustainable approach for the production of natural compounds.This review focuses on the biosynthetic pathways of mushroom originated natural compounds and microbes as the production host for the production of the above natural compounds.

关 键 词:MUSHROOM Natural compound Microbes Synthetic biology Metabolic engineering 

分 类 号:R932[医药卫生—生药学] Q819[医药卫生—药学]

 

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