3,4-seco-Isopimarane and 3,4-seco-pimarane diterpenoids from Callicarpa nudiflora  

作　　者：HUANG Hang TANG Chun-Ping KE Chang-Qiang SHU Ren-Geng YE Yang 

机构地区：[1]State Key Laboratory of Drug Research and Natural Products Chemistry Department,Shanghai Institute of Materia Medica,Chinese Academy of Sciences,Shanghai 201203,China [2]School of Pharmacy,Jiangxi University of Traditional Chinese Medicine,Nanchang 330004,China [3]School of Life Science and Technology,Shanghai Tech University,Shanghai 201210,China

出　　处：《Chinese Journal of Natural Medicines》2021年第8期632-640,共9页中国天然药物（英文版）

基　　金：supported from the China National Key R&D Program(Nos.2017YFE0195100 and 2018YFC.707000);the National Natural Science Foundation of China(Nos.21920102003 and 81903485)。

摘　　要：A phytochemical investigation was carried out on the extract of a medicinal plant Callicarpa nudiflora,resulting in the characterization of five new 3,4-seco-isopimarane(1-5)and one new 3,4-seco-pimarane diterpenoid(6),together with four known compounds.The structures of the new compounds were fully elucidated by extensive analysis of MS,1 D and 2 D NMR spectroscopic data,and time-dependent density functional theory(TDDFT)calculation of electronic circular dichroism(ECD)spectra,and DFT calculations for NMR chemical shifts and optical rotations.

关 键 词：Callicarpa nudiflora 3 4-seco-Isopimarane 3 4-seco-Pimarane TDDFT-ECD DFT calculation 

分 类 号：R284[医药卫生—中药学]