应用磁共振DWI序列ADC值及骨髓对比率诊断脊椎转移瘤的可行性研究  

Feasibility Stud of Using MRI DWI Sequence ADC Value and Bone Marrow Contrast Ratio to Diagnose Spinal Metastases

作　　者：卿培东[1] 曹云[1] 徐剑峰[1] 邓海涛[1] 李明凡 QING Pei-dong;CAO Yun;XU Jian-feng;DENG Hai-tao;LI Ming-fan(Department of Spinal Surgery,Mianyang Orthopedic Hospital,Mianyang 621000,Sichuan Province,China)

机构地区：[1]绵阳市骨科医院脊柱外科,四川绵阳621000

出　　处：《中国CT和MRI杂志》2021年第10期171-173,共3页Chinese Journal of CT and MRI

基　　金：四川省卫生和计划生育委员普及应用项目(17PJ139)。

摘　　要：目的分析应用磁共振弥散加强成像(DWI)序列表观弥散系数(ADC)值及骨髓对比率诊断脊椎转移瘤的可行性。方法选取本院2017年3月至2018年9月收治的42例脊椎转移瘤患者作为研究对象,将42例脊椎转移瘤作为脊椎转移瘤组,随后选取同期在本院接受治疗的42例非脊椎转移瘤患者作为非脊椎转移瘤组,分析其影像学特征,测量其ADC值和骨髓对比率。结果磁共振成像(MRI)检查显示病灶在T_(1)WI上呈低信号,T_(2)WI上呈低或稍高信号,T_(1)WI(f)和DWI序列上呈明显高信号,增强扫描轻度或无明显强化;脊髓转移瘤组患者的ADC值明显高于非脊椎转移瘤组(P<0.05),另外MRI检查结果还发现邻近转移瘤正常椎体的ADC值为0.65±0.26,明显低于脊椎转移瘤组的ADC值(P<0.05)。MRI检查DWI序列扫描上病灶的骨髓对比率明显高于FSE T_(1)WI(f)序列(P<0.05)。结论MRI检查可有效显示脊椎转移瘤的影像学特点,结合DWI的ADC值与骨髓对比率可有效对椎体的弥散特征进行量化,提高脊髓转移瘤的诊断和鉴别诊断能力。Objective To analyze the feasibility that apparent dispersion coefficient(ADC)values of diffusionweighted imaging(DWI)sequence in magnetic resonance imaging and bone marrow contrast ratio are used to diagnose spinal metastatic tumor.Methods 42 patients with spinal metastatic tumors admitted to our hospital from March 2017 to September 2018 were selected.42 patients with spinal metastatic tumors were included as the spinal metastatic tumor group,and 42 patients without spinal metastatic tumors who were treated in our hospital at the same time were selected as the non-spinal metastatic tumor group,and their imaging characteristics were analyzed.ADC values and bone marrow contrast ratios were measured.Results Magnetic Resonance Imaging(MRI)showed that the lesion showed a low signal on T_(1)WI,a low or slightly higher signal on T_(2)WI,a significantly higher signal on T_(1)WI(f),and DWI sequences,and the enhanced scan showed mild or no significant enhancement.The ADC value of patients in the spinal metastatic tumor group was significantly higher than in the non-spinal metastatic tumor group(P<0.05).In addition,the MRI results showed that the ADC value of the normal vertebral body adjacent to the metastatic tumor was(0.65±0.26),which was significantly lower than that in the spinal metastatic tumor group(P<0.05).The bone marrow contrast ratio of the lesions on the DWI sequence scan in MRI was significantly higher than that on the FSE T_(1)WI(f)sequence(P<0.05).Conclusion MRI examination can effectively display the imaging features of spinal metastatic tumors.The combination of ADC value of DWI and bone marrow contrast ratio can effectively quantify the diffuse characteristics of vertebral bodies and improve the diagnosis and differential diagnosis for spinal cord metastasis.

关 键 词：磁共振成像 弥散加强成像 表观弥散系数 骨髓对比率 

分 类 号：R445.2[医药卫生—影像医学与核医学] R738.1[医药卫生—诊断学]