菘蓝属植物化学成分及药理作用研究进展  

Research Progress on Chemical Constituents and Pharmacological Effects of Isatis

作　　者：杨立国 王琪 苏都那布其 包晓华[1,2] 王秀兰 奥·乌力吉[1,2] YANG Liguo;WANG Qi;Sudunabuqi;BAO Xiaohua;WANG Xiulan;AO·Wuliji(College of Mongolian Medicine and Pharmacy,Inner Mongolia University for Nationalities,Tongliao 028000,China;Mongolian Medicine Engineering Technology Institute of Inner Mongolia,Tongliao 028000,China;Keerqin District Branch of Tongliao Ecological Environment Bureau,Tongliao 028000,China)

机构地区：[1]内蒙古民族大学蒙医药学院,内蒙古通辽028000 [2]内蒙古蒙医药工程技术研究院,内蒙古通辽028000 [3]通辽市生态环境局科尔沁区分局,内蒙古通辽028000

出　　处：《中国现代应用药学》2021年第16期2039-2048,共10页Chinese Journal of Modern Applied Pharmacy

基　　金：内蒙古民族大学博士科研启动基金项目(BS464);内蒙古自治区自然科学基金项目(2019BS08017)。

摘　　要：菘蓝属植物在中国药用历史悠久,其中菘蓝的根和叶即为板蓝根和大青叶。该属植物化学成分多样,主要包括生物碱类、硫代葡萄糖苷类、木脂素类、黄酮类等,具有抗菌、抗病毒、抗内毒素、抗肿瘤、抗炎、免疫增强等药理作用。本文对近40年来国内外有关菘蓝属植物化学成分和药理作用的文献进行系统的总结,为该属植物的进一步研究开发提供参考。Isatis has a long history of medicinal use in China,among which the roots and leaves of Isatis indigotica are Banlangen and Daqingye.Genus Isatis plants have a variety of chemical constituents,including alkaloids,glucosinolates,lignans and flavonoids,which have the pharmacological activities of antibacterial,antivirus,antiendotoxin,antitumor,anti-inflammatory,immune regulation,etc.The paper made a systematic summary about research on the chemical constituents and pharmacological effects of Isatis in China and abroad for forty years to provide the references for further studies.

关 键 词：菘蓝属 化学成分 生物碱类 硫代葡萄糖苷类 木脂素类 黄酮类 药理作用 

分 类 号：R284.1[医药卫生—中药学]