四联疗法联合康复新液治疗幽门螺杆菌相关性溃疡患者的效果  

Effect of quadruple therapy combined with Kangfuxin Liquid in patients with Helicobacter pylori-related ulcer

作　　者：易珍 YI Zhen(Department of Gastroenterology,Shangrao Municipal Hospital,Jiangxi Province,Shangrao 334000,China)

机构地区：[1]江西省上饶市立医院消化内科,江西上饶334000

出　　处：《中国当代医药》2021年第25期56-58,62,共4页China Modern Medicine

基　　金：江西省上饶市科技局指导性科技计划项目(20171CZD18)。

摘　　要：目的探究四联疗法与康复新液联合治疗幽门螺杆菌相关性溃疡疾病的效果。方法选取2018年3月—2020年3月上饶市立医院收治的56例胃及十二指肠球部溃疡患者作为研究对象,按照随机数字表法分为观察组与对照组,每组各28例。对照组给予四联疗法进行治疗,观察组采用四联康复疗法联合康复新液进行治疗。比较两组的治疗总有效率、幽门螺杆菌根除率与复发率、不良反应总发生率。结果治疗后,观察组的总有效率为92.86%,高于对照组的67.87%,差异有统计学意义(P<0.05);观察组的幽门螺杆菌清除率为96.43%,高于对照组的71.42%,差异有统计学意义(P<0.05);观察组的复发率为7.14%,低于对照组的28.57%,差异有统计学意义(P<0.05);观察组的不良反应总发生率为7.14%,低于对照组的28.57%,差异有统计学意义(P<0.05)。结论幽门螺杆菌相关性溃疡患者采取四联疗法联合康复新液治疗,可明显提升临床疗效,提高幽门螺杆菌,降低幽门螺杆菌的复发率,同时有效降低了不良反应的发生率,临床应用价值显著。Objective To explore the effect of quadruple therapy combined with Kangfuxin Liquid in patients with Helicobacter pylori-related ulcer.Methods A total of 56 patients with gastric and duodenal bulb ulcers admitted to the Shangrao Municipal Hospital from March 2018 to March 2020 as the research objects,and divided into the control group and the observation group according to the random number table method,with 28 cases in each group.The control group was treated with quadruple therapy,and the observation group as treated with quadruple therapy combined with Kangfuxin Liquid.The total effective rate,Helicobacter pylori eradication rate and recurrence rate,and total incidence of adverse reactions were compared between the two groups.Results After the treatment,the total effective rate of the observation group was 92.86%,which was higher than 67.87%of the control group,and the differences were statistically significant(P<0.05).The Helicobacter pylori clearance rate of the observation group was 96.43%,which was higher than 71.42%of the control group,and the differences were statistically significant(P<0.05).The recurernce rate of the observation group was 7.14%,which was lower than 28.57%of the control group,and the differences were statistically significant(P<0.05).The total incidence of adverse reactions of the observation group was 7.14%,lower than 28.57%of the control group,and the differences were statistically significant(P<0.05).Conclusion In patients with Helicobacter pylori associated ulcer disease,quadruple therapy combined with Kangfuxin Liquid could significantly improve the clinical efficacy,improve Helicobacter pylori,reduce the recurrence rate of Helicobacter pylori,and effectively reduce the incidence of adverse reactions,and the clinical application value is significant.

关 键 词：四联疗法 康复新液 幽门螺杆菌相关性溃疡 临床效果 

分 类 号：R573.1[医药卫生—消化系统]