高频彩超在继发性甲状旁腺功能亢进症外科治疗中的应用  

Application of high-frequency color Doppler ultrasound in surgical treatment of secondary hyperparathyroidism

作　　者：熊剑丁 饶珣坚 谢海涛[1] 陈以标 赖明亮[1] XIONG Jian-ding;RAO Xun-jian;XIE Hai-tao;CHEN Yi-biao;LAI Ming-liang(Department of Otolaryngology,Head and Neck Surgery,Fengcheng People′s Hospital,Jiangxi Province,Fengcheng 331100,China;Department of Ultrasound,Fengcheng People′s Hospital,Jiangxi Province,Fengcheng 331100,China)

机构地区：[1]江西省丰城市人民医院耳鼻咽喉头颈外科,江西丰城331100 [2]江西省丰城市人民医院超声科,江西丰城331100

出　　处：《中国当代医药》2021年第26期77-79,83,共4页China Modern Medicine

基　　金：江西省卫生健康委科技计划项目(20204777)。

摘　　要：目的探讨高频彩超在继发性甲状旁腺功能亢进症(SHPT)外科治疗中的应用效果。方法选取2018年12月至2020年6月丰城市人民医院收治的40例SHPT患者作为研究对象,均行高频彩超检查,再行甲状旁腺切除术及术后病理诊断。观察其手术病理结果、超声结果及其准确度、灵敏度和特异度,比较术前与术后血清全段甲状旁腺激素(iPTH)、钙(Ca)、磷(P)。结果40例患者共切除结节133枚,病理诊断甲状旁腺增生118枚、淋巴结8枚、甲状腺结节3枚、异位胸腺2枚、脂肪组织2枚。超声结果显示甲状旁腺增大或增生103枚,以病理学诊断为金标准,超声诊断的准确度为78.20%、灵敏度81.36%、特异度为53.33%。40例患者术后血清iPTH、Ca、P均低于术前,差异有统计学意义(P<0.05)。结论高频彩超应用于SHPT术前检查中准确度和灵敏度均较高,为临床治疗和术前定位提供了重要的参考依据。Objective To investigate the application effect of high-frequency color Doppler ultrasound in surgical treatment of secondary hyperparathyroidism(SHPT).Methods A total of 40 patients with SHPT admitted to Fengcheng People′s Hospital from December 2018 to June 2020 were selected as the research objects.All patients were given high-frequency color ultrasound examination,parathyroidectomy and postoperative pathological diagnosis.The operative pathological results,ultrasonographic results and their accuracy,sensitivity and specificity were observed.The serum intact parathyroid hormone(iPTH),calcium(Ca)and phosphorus(P)were compared between preoperative and postoperative.Results A total of 133 nodules were resected in 40 patients,and 118 parathyroid hyperplasia,eight lymph nodes,three thyroid nodules,two ectopic thymus glands,and two adipose tissue were pathologically diagnosed.The results of ultrasonography showed 103 enlargement or hyperplasia of parathyroid glands.The pathological diagnosis was considered as the golden standard.The accuracy,sensitivity and specificity of ultrasonic diagnosis were 78.20%,81.36%and 53.33%.The serum iPTH,Ca and P of 40 patients after operation were lower than those before operation,the differences were statistically significant(P<0.05).Conclusion The application of high-frequency color Doppler ultrasound in the preoperative examination of SHPT has high accuracy and sensitivity,which provides an important reference basis for clinical treatment and preoperative positioning.

关 键 词：高频彩超 继发性 甲状旁腺功能亢进症 外科治疗 

分 类 号：R582.1[医药卫生—内分泌]