Effects of Cotrimoxazole Prophylaxis Initiation and Discontinuation on Mortality and Attrition Rates among HIV Patients Who Initiate ART in Southwest China:An Observational Cohort Study  

作　　者：ZHU Jin Hui RUAN Yu Hua PAN Stephen YANG Wen Min ZHU Qiu Ying CHEN Huan Huan SHEN Zhi Yong LAN Guang Hua XING Hui SHAO Yi Ming LI Li Ming 

机构地区：[1]School of Public Health,Peking University,Beijing 100191,China [2]Guangxi Center for Disease Control and Prevention,Nanning 530028,Guangxi,China [3]State Key Laboratory of Infectious Disease Prevention and Control(SKLID),Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases,Chinese Center for Disease Control and Preventio n(China CDC),Beijing 100032,China [4]Department of Health and Environ mental Sciences,Xi'an Jiaotong-Liverpool University,Suzhou 215123,Jiangsu,China

出　　处：《Biomedical and Environmental Sciences》2021年第8期646-649,共4页生物医学与环境科学（英文版）

基　　金：the Guangxi Medical and Health Project[Z20170126];the National Natural Science Foundation of China[Grant numbers 11971479,81502862,81460510,81360442,and 91546203];Guangxi Science and Technology Bureau[Grant number AB16380213];Guangxi Bagui Honor Scholarship,Ministry of Science and Technology of China[2018ZX10721102-006 and 2017ZX10201101];Guangxi Key Laboratory of AIDS Prevention Control and Translation,and Chinese State Key Laboratory of Infectious Disease Prevention and Control.

摘　　要：Combination antiretroviral therapy(ART)reduced AIDS-related mortality and increased survival among patients living with HIV by interrupting HIV replication,enhancing immune recovery,and preventing the onset of opportunistic infections[1].In China,ART has rapidly been scaled up since the beginning of the National Free Antiretroviral Treatment Program(NFATP)in 2003[2].By the end of 2016,489,411 individuals diagnosed with HIV were receiving free antiretroviral treatment in China.China is firmly committed to reducing overall AIDS-related mortality and HIV incidence within the country.However,similar to other low-and middle-income countries,the NFATP is challenged by high mortality and attrition shortly after patients initiate ART[3].

关 键 词：MORTALITY Observation CONTINUATION 

分 类 号：R512.91[医药卫生—内科学]