儿童特应性皮炎与注意缺陷多动障碍的关联性及其潜在机制的研究进展  

Research progress on interrelation between atopic dermatitis and attentiondeficit hyperactivity disorder and its mechanism

作　　者：任文静 徐阳春[2] 黎萍(指导)[1] REN Wen-Jing;XU Yang-Chun;LI Ping(Department of Developmental Pediatrics,the Second Hospital of Jilin University,Changchun 130041,China)

机构地区：[1]吉林大学第二医院发育儿科,长春130041 [2]吉林大学第二医院皮肤科,长春130041

出　　处：《中国免疫学杂志》2021年第16期2047-2048,F0003,F0004,共4页Chinese Journal of Immunology

基　　金：吉林省教育厅科学研究项目(JJKH20211233kj)资助。

摘　　要：特应性皮炎(AD)是一种以慢性炎症为主要特征的过敏性疾病。近年来,其与注意缺陷多动障碍(ADHD)的患病率同时呈上升趋势,二者的流行病学关联及病理生理联系已经引起了广泛关注。本文旨在通过回顾文献,阐明AD与ADHD的关联性及其潜在机制,关注二者相互作用关系及潜在的作用靶点,对患儿的全面医学管理和药物开发具有重要意义。Atopic dermatitis(AD)is an allergic disease characterized by chronic inflammation. In recent years,AD and attention deficit hyperactivity disorder(ADHD)exhibit a parallel rise in global prevalence,meanwhile their epidemiological and pathophysiological interrelation has attracted widespread attention. The purpose of this review is to clarify the interaction between AD and ADHD,and its potential targets,which is of great significance for the comprehensive medical management of children with these diseases and drug development.

关 键 词：特应性皮炎 注意缺陷多动障碍 免疫 肠道菌群 共患病 

分 类 号：R758.2[医药卫生—皮肤病学与性病学]