红细胞分布宽度对非ST段抬高型心肌梗死患者病情严重程度的预测研究  

Red cell distribution width predicts the severity of non-ST-elevation myocardial infarction in patients

作　　者：汪剑锋 陈培锦 张国恺 沈阳 Wang Jianfeng;Chen Peijin;Zhang Guokai;Shen Yang(Department of Cardiology,Chaozhou People's Hospital,Chaozhou 521000,Guangdong Province,China)

机构地区：[1]潮州市人民医院心血管内科,广东省521000

出　　处：《中国基层医药》2021年第9期1281-1285,共5页Chinese Journal of Primary Medicine and Pharmacy

基　　金：广东省潮州市卫生健康局科研项目(2019064)。

摘　　要：目的分析非ST段抬高型心肌梗死患者红细胞分布宽度(RDW)与病情严重程度的关系。方法选取潮州市人民医院2019年6月至2020年6月治疗的非ST段抬高型心肌梗死患者70例为观察组,另选取该院同期治疗的ST段抬高型心肌梗死患者70例为对照组,均行心电图、血液生化指标检查,比较两组RDW,分析RDW与病情严重程度的关系。结果观察组RDW为(14.60±1.00)%,明显高于对照组的(13.06±1.70)%,差异有统计学意义(t=5.884,P=0.012)。观察组冠状动脉血栓检出率为70.00%(49/70),高于对照组的50.00%(35/70),差异有统计学意义(χ^(2)=7.563,P=0.002)。以RDW为变量,对观察组进行受试者工作特征曲线(ROC曲线)分析,曲线下面积为0.649(95%CI 0.546~0.753,P=0.006);当RDW临界值为14%时,RDW对非ST段抬高型心肌梗死患者的敏感性、特异性分别为73%、59%。RDW与心肌肌钙蛋白I呈正相关(r=0.19,P=0.006)。结论在非ST段抬高型心肌梗死患者中,RDW升高与心肌损伤和心肌肌钙蛋白I水平升高均有关,RDW可作为预测非ST段抬高型心肌梗死患者病情严重程度的有效指标。Objective To analyze the relationship between red cell distribution width(RDW)and disease severity in patients with non-ST-elevation myocardial infarction.Methods Seventy patients with non-ST-elevation myocardial infarction who received treatment in Chaozhou People's Hospital from June 2019 to June 2020 were included in the observation group.An additional 70 patients with ST-elevation myocardial infarction who concurrently received treatment in the same hospital were included in the control group.All patients underwent electrocardiography and blood biochemical index examination.RDW was compared between the observation and control groups.The relationship between RDW and the severity of non-ST-elevation myocardial infarction was analyzed.Results RDW in the observation group was significantly higher than that in the control group[(14.60±1.00)%vs.(13.06±1.70)%,t=5.884,P=0.012).The detection rate of coronary artery thrombosis in the observation group was significantly higher than that in the control group[70.00%(49/70)vs.50.00%(35/70),χ^(2)=7.563,P=0.002].In the observation group,the area under the receiver operating characteristic(ROC)curve plotted taking RDW as the variable was 0.649(95%CI 0.546-0.753,P=0.006).When the critical value of RDW was 14%,the sensitivity and specificity of RDW in the prediction of non-ST-elevation myocardial infarction were 73%and 59%respectively.RDW was positively correlated with cardiac troponin I level(r=0.19,P=0.006).Conclusion In patients with non-ST-elevation myocardial infarction,the increase in RDW is related to myocardial injury and the increase in cardiac troponin I level.RDW can be used as an effective index to predict the severity of non-ST-elevation myocardial infarction.

关 键 词：非ST段抬高型心肌梗死 ST段抬高型心肌梗死 心电描记术 红细胞指数 冠状动脉血栓形成 肌钙蛋白I ROC曲线 预测 

分 类 号：R542.22[医药卫生—心血管疾病]