恰米烷型倍半萜——结构和生物活性  

Cumethane type sesquiterpenes structure and bioactivity

作　　者：冯涛[1] 刘吉开[1] FENG Tao;LIU Ji-kai(School of Pharmaceutical Sciences,South-Central University for Nationalities,Wuhan 430074,China)

机构地区：[1]中南民族大学药学院,湖北武汉430074

出　　处：《云南民族大学学报（自然科学版）》2021年第5期436-440,共5页Journal of Yunnan Minzu University:Natural Sciences Edition

基　　金：国家自然科学基金(81872762)

摘　　要：恰米烷是一类具有螺[5,5]十一烷双环结构的特殊倍半萜类型,因其特殊的结构类型和良好的生物活性日渐成为天然药物化学的研究热点.对从不同来源的恰米烷型倍半萜的结构及其生物活性进行综述,发现恰米烷型倍半萜活性与C-4/C-7有过氧桥环有关,这对今后探究不同结构的构效关系具有极大意义.Chamethane is a kind of special sesquiterpene with spiral[5,5]undecane bicyclic structure.Because of its special structure and good biological activity,it has become the focus of natural pharmaceutical chemistry research.In this review,the structures and biological activities of the camethane type sesquiterpenes from different sources are reviewed.

关 键 词：天然产物 恰米烷型倍半萜 生物活性 

分 类 号：TQ455.4[化学工程—农药化工]