Synthesis of Phenanthridine and Quinoxaline Derivatives via Copper-Catalyzed Radical Cyanoalkylation of Cyclobutanone Oxime Esters and Vinyl Azides  

作　　者：Qi Liang Long Lin Guodong Li Xianqiang Kong Bo Xu 

机构地区：[1]Key Laboratory of Science and Technology of Eco-Textiles,Ministry of Education,College of Chemistry,Chemical Engineering and Biotechnology,Donghua University,Shanghai,201620 China [2]School of Chemical Engineering and Materials,Changzhou Institute of Technology,No.666 Liaohe Road,Changzhou,Jiangsu,213032 China

出　　处：《Chinese Journal of Chemistry》2021年第7期1948-1952,共5页中国化学（英文版）

基　　金：We are grateful to the National Natural Science Foundation of China(No.NSFC-21871046).

摘　　要：Main observation and conclusion A copper-catalyzed radical cyclization of cyclobutanone oxime esters and vinyl azide is described.This method provides facile access to cyanoalkyl-substituted phenanthridines and quinoxalines with excellent isolated yields.Moreover,these reactions proceed under mild conditions with a board substrate scope and excellent functional group tolerance.

关 键 词：CYCLIZATION Radical reactions Cyanoalkylation Vinyl azides Copper 

分 类 号：O62[理学—有机化学]