A GSH-responsive PET-based fluorescent probe for cancer cells imaging  

作　　者：Xue Li Huaying Wang Youhui Zhang Qianyong Cao Yong Chen 

机构地区：[1]Chemical College,Nanchang University,Nanchang 330031 China [2]Jiangxi Key Laboratory for Microscale Interdisciplinary Study,Institute for Advanced Study.Nanchang University,Nanchang 330031,China

出　　处：《Chinese Chemical Letters》2021年第4期1541-1544,共4页中国化学快报（英文版）

基　　金：supported by the National Nature Science Foundation of China(Nos.21762028 and 21462027);the Nature Science Foundation of Jiangxi Province of China(No.20172BCB22007),which are greatly acknowledged by the authors。

摘　　要：An efficient PET-based probe,in which the ferrocene quencher and the naphthalimide fluorophore are linked by a disulfide bond,has been developed.This probe can be activated by GSH with fluorescence a turn-on response for blocking the PET process.In addition,it was successfully applied for distinguishing cancer cells from normal cells。

关 键 词：GSH sensing Photoinduced electron transfer Fluorescent sensor Cancer cells imaging 

分 类 号：O657.3[理学—分析化学] R730.4[理学—化学]