铜催化噁唑硼烷氢转移还原亚胺化合物  

Copper Catalyzed Transfer Hydrogenation of Imines by 1,3,2-Oxazaborolidine Complex

作　　者：宋浩 郭良程 王洋 刘亚鑫 任小丽 张家莉 孙茂苹 周太刚 SONG Hao;GUO Liang-cheng;WANG Yang;LIU Ya-xin;REN Xiao-li;ZHANG Jia-li;SUN Mao-ping;ZHOU Tai-gang(College of Chemistry and Chemical Engineering, Southwest Petroleum University, Chengdu 610500, China;State Key Laboratory of Oil and Gas Reservoir Geology and Exploitation,Southwest Petroleum University, Chengdu 610500, China;Sinopec Jianghan Salt Chemical Hubei Co.Ltd., Qianjiang 433100, China)

机构地区：[1]西南石油大学化学化工学院,四川成都610500 [2]西南石油大学油气藏地质及开发工程国家重点实验室,四川成都610500 [3]中石化江汉盐化工湖北有限公司,湖北潜江433100

出　　处：《合成化学》2021年第9期721-727,共7页Chinese Journal of Synthetic Chemistry

基　　金：国家自然科学基金青年基金资助项目(21602184);四川省科技计划资助(2021YFH0161)。

摘　　要：以三氟甲烷磺酸铜为催化剂,1,3,2-噁唑硼烷络合物(由乙醇胺与BH3·THF反应制得)作为氢源,在温和反应条件下(80℃,24 h),实现了铜催化的亚胺氢转移还原,合成了21个胺类化合物,产率62%~85%,其结构通过^(1)H NMR和^(13)C NMR确证。The copper trifluoromethane sulfonate was used as a metal catalyst,1,3,2-oxazaborolidine complex(prepared by the reaction of ethanolamine with BH3·THF)was used as the hydrogen source.Under mild conditions(80℃,24 h),copper catalyzed hydrogen transfer reduction of imine.Twenty-one amine derivatives were synthesized in 62%~85% yields,its structure was confirmed by ^(1)H NMR and ^(13)C NMR.

关 键 词：铜催化 亚胺 胺 1 3 2-噁唑硼烷 氢转移 合成 

分 类 号：O625.6[理学—有机化学]