复方板蓝根颗粒联合恩替卡韦治疗学生慢性乙型肝炎临床观察  

Control Effect of Compound Banlangen GranulesCombined with Entecavir on Chronic Hepatitis B Among Students

作　　者：张文 ZHANG Wen(Center for Disease Control and Prevention in Shunhe Hui District,Kaifeng 475000,Henan,China)

机构地区：[1]开封市顺河回族区疾病预防控制中心,河南开封475000

出　　处：《实用中医内科杂志》2021年第8期102-104,共3页Journal of Practical Traditional Chinese Internal Medicine

基　　金：河南省卫生政策研究项目(20171966)。

摘　　要：目的探究学生慢性乙型肝炎采用复方板蓝根颗粒联合恩替卡韦的控制效果分析。方法选择医院2018年1月—2020年12月收治的学生慢性乙型肝炎患者共92例,以简单随机法分为对照组和观察组各46例患者,对照组患者采取恩替卡韦进行抗病毒治疗,观察组患者采取复方板蓝根颗粒联合恩替卡韦治疗,探讨两组治疗前后中医证候积分变化,同时了解两组对疾病的一个控制效果和患者的肝功能情况。结果治疗实施前,收集患者的中医证候积分以及对患者的肝功能指标进行测定,发现两组患者的中医证候积分对比,无统计学意义,两组患者各项肝功能指标均无差异(P>0.05)。治疗后,观察组患者的各项中医证候积分比较,均优于对照组(P<0.05),对比数据存在统计学意义。观察组患者的疾病控制效果优于对照组(P<0.05),对比数据存在统计学意义。观察组患者的各项肝功能指标均优于对照组(P<0.05),对比数据存在统计学意义。结论在学生慢性乙型肝炎的治疗中,单纯采取恩替卡韦,可在一定程度上改善患者的病情,但并不显著,而在应用恩替卡韦的基础上联合复方板蓝根颗粒,具有提升治疗效果的作用,从而促进患者临床症状消失或缓解,进一步改善患者的各项肝功能指标,其临床价值较高,值得推广。Objective To explore the control effect of Compound Banlangen Granules combined with entecavir on chronic hepatitis B among students.Methods A total of 92 students with chronic hepatitis B in our department from January 2018 to December 2020 were selected and randomly divided into control group and observation group with 46 cases in each group. The control group was treated with entecavir, while the observation group was treated with Compound Banlangen Granules combined with entecavir. At the same time, the control effect of the two groups on the disease and the liver function of the patients were investigated. Results Before the implementation of the treatment, the TCM symptom scores of the patients were collected and the liver function indexes of the patients were measured. It was found that the TCM symptom scores of the two groups were not statistically significant, and there was no difference in the liver function indexes of the two groups(P>0.05). After treatment, the TCM symptom scores of the observation group were better than those of the control group(P<0.05). The disease control effect of the observation group was better than that of the control group(P<0.05). The liver function indexes of the observation group were better than those of the control group(P<0.05). Conclusion In the treatment of students with chronic hepatitis B, entecavir alone can improve the patients’ condition to a certain extent, but it is not significant. On the basis of entecavir combined with Compound Banlangen Granules, it can improve the treatment effect, promote the disappearance or remission of clinical symptoms, and further improve the liver function indexes of patients. It has high clinical value and is worthy of promotion.

关 键 词：慢性乙型肝炎 恩替卡韦 联合 效果 复方板蓝根颗粒 中医证候积分 肝功能 对比 

分 类 号：R512.62[医药卫生—内科学]