胰岛素治疗与体质量管理:从指南角度看基础胰岛素应用  

Insulin Medication and Body Weight Management:Application of Basic Insulin from the Perspective of Guidelines

作　　者：邹大进[1] ZOU Dajin(Shanghai Tenth People's Hospital,Tenth People's Hospital of Tongji University,Shanghai 200072,China.)

机构地区：[1]上海市第十人民医院,同济大学附属第十人民医院,上海200072

出　　处：《药品评价》2021年第15期897-900,共4页Drug Evaluation

摘　　要：胰岛素治疗是控制高血糖的重要手段。从新诊断高血糖患者的早期强化到口服降糖药治疗不佳时的补充治疗,以及病程晚期的胰岛素替代治疗,均给患者带来了多重获益。然而,胰岛素治疗往往会增加2型糖尿病(T2DM)患者的体质量,体质量增加会增加血糖控制的难度。因此,降糖与体质量管理并举对胰岛素治疗提出了更高要求。本文将依据最新指南,阐述胰岛素降糖与体质量管理同时兼顾的重要意义,以期为广大临床医师提供参考。Insulin therapy is a pivotal method to control hyperglycemia.From early intensive treatment in newly-diagnosed patients with hyperglycemia to supplementary treatment when oral hypoglycemic drugs fail to control,or insulin replacement therapy in the late stage of diabetes,all patients could benefit from insulin treatments.However,insulin therapy often increase the body weight and the difficulty of glucose control in patients with type 2 diabetes.Therefore,both hypoglycemic and weight management put forward further requirements for insulin.According to the latest guidelines,this article will elaborate the significance of synchronizing targeting of blood glucose and weight management,in order to provide reference for the numerous clinicians.

关 键 词：糖尿病 2型 体质量 基础胰岛素 地特胰岛素 指南 

分 类 号：R587.1[医药卫生—内分泌]