消旋卡多曲联合补锌治疗小儿轮状病毒肠炎的疗效观察  

Observation on the efficacy of racemic cardotriol combined with zinc supplementation in the treatment of pediatric rotavirus enteritis

作　　者：杨安常 YANG Anchang(Department of Pediatrics,the Surabaya District of Jining First People's Hospital,Jining,Shandong,273200,China)

机构地区：[1]济宁市第一人民医院泗水院区儿科,山东济宁273200

出　　处：《当代医学》2021年第27期67-69,共3页Contemporary Medicine

摘　　要：目的分析消旋卡多曲联合补锌治疗小儿轮状病毒肠炎的疗效观察。方法选取2018年9月至2019年8月本院收治的轮状病毒肠炎患儿82例为研究对象,随机单双数法分为两组,各41例。对照组采用基础治疗,观察组采用消旋卡多曲联合补锌治疗,比较两组临床疗效、症状改善时间及心肌酶水平。结果观察组治疗总有效率为97.56%(40/41),高于对照组的80.48%(33/41),差异有统计学意义(P<0.05);观察组平均退热、脱水纠正等症状改善时间均短于对照组,差异有统计学意义(P<0.05);观察组肌酸激酶(CK)、肌酸磷化脢-同功脢(CK-MB)、谷丙转氨酶(AST)水平高于对照组,差异有统计学意义(P<0.05)。结论消旋卡多曲联合补锌治疗轮状病毒肠炎患儿疗效显著,可缩短临床症状改善时间,降低心肌酶水平,具有临床应用价值。Objective To analyze the effect of racemic cardol combined with zinc supplementation in the treatment of pediatric rotavirus enteritis.Methods A total of 82 children with rotavirus enteritis treated in our hospital from September 2018 to August 2019 were selected as the research subjects.They were divided into two groups according to random odd and even number method,with 41 cases in each group.The control group received basic treatment,and the observation group received racecardotrel combined with zinc supplement.The clinical efficacy,symptom improvement time and myocardial enzyme level were compared between the two groups.Results The total effective rate in the observation group was97.56%(40/41),which was higher than 80.48%(33/41)in the control group,the difference was statistically significant(P<0.05).The average improvement time of symptoms such as fever and dehydration correction in the observation group were shorter than those in the control group,the difference was statistically significant(P<0.05).The levels of creatine kinase(CK),creatine phosphase(CK-MB)and alanine transaminase(AST)in the observation group were higher than those in the control group,with statistical significance(P<0.05).Conclusion Racecadotril combined with zinc supplementation is effective in the treatment of children with rotavirus enteritis can shorten the improvement time of clinical symptoms and reduce the level of myocardial enzymes and has clinical application value.

关 键 词：消旋卡多曲 补锌治疗小儿轮状病毒肠炎 症状改善时间 心肌酶 

分 类 号：R725.1[医药卫生—儿科]