The Effect of Carbohydrate Drinks Before Painless Colonoscopy on Hemodynamic Stability  

作　　者：Ling-Xia Li Dong-Hua Zhang Hao Zhang Ping Jiang Guang-Chao Wang Ying Yao 

机构地区：[1]Naval Military Medical University,Shanghai,China. [2]Department of Biochemistry and Psychopharmacology,Shanghai Mental Health Center,Shanghai Jiaotong University School of Medicine,Shanghai,China. [3]Shanghai Key Laboratory of Psychotic Disorders,Shanghai Mental Health Center,Shanghai Jiao tong University School of Medicine,Shanghai,China.

出　　处：《Psychosomatic Medicine Research》2021年第2期53-60,共8页心身医学研究

基　　金：the appropriate Institutional Review Board and Changhai Hospital Ethics Committee(Shanghai,China;approval no.CHEC2018-080);the Chinese Clinical Trial Registry(www.chictr.org.cn;identifier:ChiCTR1800015899).

摘　　要：Purpose:Elderly patients underwent a sharp decline in blood pressure after the induction of anesthesia and were subjected to many kinds of discomfort before and after painless colonoscopy.The aim was to investigate if the oral intake of carbohydrate drinks(CHD)alleviated side effects during colonoscopy.Methods:Sixty patients were randomly assigned to the CHD group(A)to receive preoperative CHD,the glucose group(B)to receive preoperative sugar drink,and the fasting control group(C)to undergo preoperative fasting for at least 10 h.The primary outcomes were hemodynamic data before anesthesia(T1),one(T2)and five(T3)minutes after induction,the beginning(T4)and end(T5)of colonoscopy.The secondary outcomes were hunger,thirst,stomach discomfort,anxiety,and fatigue in patients,who were assessed using a visual analog scale.Additionally,postoperative parameters such as blood glucose level were evaluated.Results:Intraoperative hemodynamics(data on T2,T3,and T4)including systolic blood pressure,diastolic blood pressure,mean arterial pressure,and heart rate was higher in the CHD group than in the glucose and fasting group(P<0.01).Preoperatively alleviated feelings of hunger and thirst were found to be in the CHD group compared with the glucose(P<0.01 in hunger and P<0.05 in thirst)and fasting group(P<0.01).The blood glucose level in the CHD group was lower than that in the glucose group(P<0.01)and higher than in the fasting group(P<0.01).Critically,oral CHD did not affect the process of colonoscopy.Conclusion:Oral intake of CHD stabilizes perioperative hemodynamic change and alleviates preoperative discomfort during painless colonoscopy.

关 键 词：Carbohydrates HEMODYNAMICS Patient comfort FASTING 

分 类 号：R54[医药卫生—心血管疾病]