白及化学成分、药理作用和白及多糖提取工艺的研究进展  

Research Progress in Chemical Components and Pharmacological Actions of Bletilla striata and Extraction Technology of Its Polysaccharide

作　　者：孔伟华 徐建波 崔琦 盛振华 袁强[1] 张春椿[1] 李石清[1] KONG Weihua;XU Jianbo;CUI Qi;SHENG Zhenhua;YUAN Qiang;ZHANG Chunchun;LI Shiqing(College of Pharmaceutical Science,Zhejiang Chinese Medical University,Hangzhou 310053,China;Academy of Chinese Medical Sciences,Zhejiang Chinese Medical University,Hangzhou 310053,China)

机构地区：[1]浙江中医药大学药学院,浙江杭州310053 [2]浙江中医药大学中医药科学院,浙江杭州310053

出　　处：《中医药信息》2021年第9期69-78,共10页Information on Traditional Chinese Medicine

基　　金：浙江省中医药科技计划中医药现代化专项项目(2021ZX008);中医药行业科研专项子课题(752211A00362)。

摘　　要：白及来源于兰科植物白及的干燥块茎,具有收敛止血、消肿生肌的功效,有着悠久的应用历史。本文整理了白及的化学成分、药理活性及白及多糖提取工艺的研究概况,发现白及含有糖类、联苄类及其衍生物、菲类、二氢菲类、二氢菲呋喃类、联菲类、双菲醚类、甾体以及三萜等有效成分,主要有止血、免疫调节、促进伤口愈合、抗菌、抗炎、抗肿瘤、抗氧化、抗溃疡、促进造血、抗病毒等药理活性,白及多糖的提取方式主要有溶剂提取、超声提取、微波提取和酶辅助提取法等。Bletilla striata is the dry tuber of orchidaceae plant Bletilla striata.It has the actions of astringency and hemostasis,as well as reducing swelling and generating muscle,which has been used for a long period of time.This study reviewed the chemical components and pharmacological actions of Bletilla striata and the extraction technology of its polysaccharide.It is found that Bletilla striata contains saccharides,bibenzyls,benzyl derivatives,phenanthrenes,dihydrophenanthrenes,dihydrofurans,diphenylene,blestrin,steroid,triterpene and other chemical components.Its actions mainly include hemostasis,immune regulation,promoting wound healing,anti-bacteria,anti-inflammation,anti-tumor,anti-oxidation,anti-ulcer,promoting hematopoiesis,anti-virus and other pharmacological actions.The extraction methods mainly include solvent extraction,ultrasound extraction,microwave extraction and enzyme extraction.

关 键 词：白及 化学成分 药理作用 提取工艺 

分 类 号：R284[医药卫生—中药学] R285[医药卫生—中医学]