茵陈蒿汤加减药浴防治新生儿黄疸临床研究  

Clinical Study on Medicated Bath with Modified Yinchenhao Tang for Prevention and Treatment of Jaundice of Newborns

作　　者：李梦雅 冯丹平 杨宝顺 谢欢来 LI Mengya;FENG Danping;YANG Baoshun;XIE Huanlai

机构地区：[1]浙江中医药大学附属第一医院新生儿科,浙江杭州310006

出　　处：《新中医》2021年第17期184-187,共4页New Chinese Medicine

摘　　要：目的:观察茵陈蒿汤加减药浴防护新生儿黄疸的临床效果。方法:将110例新生儿黄疸患儿按随机数字表法分为对照组和观察组各55例。对照组给予蓝光照射和常规护理,观察组在对照组基础上给予茵陈蒿汤加减药浴,治疗5 d。比较2组临床疗效,记录黄疸消退时间、每天大便次数及每天睡眠时间,检测治疗前后经皮胆红素(TCB)、血清总胆红素(TBil)和血清直接胆红素(DBil)水平。结果:观察组临床疗效总有效率为94.55%,高于对照组80.00%,差异有统计学意义(P<0.05)。治疗前,2组TCB水平比较,差异无统计学意义(P>0.05)。治疗后1 d、2 d、3 d、4 d、5 d,2组TCB水平逐渐下降(P<0.05);观察组治疗后2 d、3 d、4 d、5 d TCB水平均低于同时间点对照组(P<0.05)。治疗前,2组TBil及DBil水平比较,差异无统计学意义(P>0.05)。治疗后,2组TBil及DBil水平较治疗前下降(P<0.05),观察组TBil及DBil水平低于对照组(P<0.05)。治疗前,2组每天大便次数和每天睡眠时间比较,差异无统计学意义(P>0.05)。治疗后,2组每天睡眠时间较治疗前增加(P<0.05),观察组每天睡眠时间高于对照组(P<0.05)。观察组黄疸消退时间短于对照组,差异有统计学意义(P<0.05)。结论:在蓝光干预基础上,给予茵陈蒿汤加减洗浴防护新生儿黄疸,能降低胆红素,促进黄疸消退,缩短病程,促进睡眠,并提高临床疗效。Objective:To observe the clinical effect of medicated bath with modified Yinchenhao tang for prevention and treatment of jaundice of newborns. Methods: A total of 110 cases of newborns with jaundice were divided into the control group and the observation group according to the random number table method,55 cases in each group. The control group was treated with blue light irradiation and routine nursing, and the observation group was additionally treated with medicated bath with modified Yinchenhao tang based on the treatment of the control group. Both groups were treated for five days. The clinical effect was compared between the two groups. The remission time of jaundice, the daily times of defecation, and the daily sleep time were recorded. Before and after treatment, levels of transcutaneous bilirubin(TCB),serum total bilirubin(TBil) and serum direct bilirubin(DBil) were measured. Results:The total clinical effective rate was 94.55%in the observation group,higher than that of 80.00% in the control group,the difference being significant(P<0.05). Before treatment,there was no significant difference being found in the comparison of TCB levels between the two groups(P>0.05). After treatment for 1,2,3,4,and 5 days,levels of TCB were gradually decreased in the two groups(P<0.05). After treatment for 2,3,4,and 5 days,TCB levels in the observation group were lower than those in the control group at the same time point(P<0.05). Before treatment,there was no significant difference being found in the comparison of TBil and DBil levels between the two groups(P>0.05). After treatment, levels of TBil and DBil in the two groups were decreased when compared with those before treatment(P<0.05),and the two levels in the observation group were lower than those in the control group(P<0.05). Before treatment,there was no significant difference being found in the comparison of the daily times of defecation and the daily sleep time between the two groups(P>0.05). After treatment,the daily sleep time in the two groups was longer tha

关 键 词：新生儿黄疸 茵陈蒿汤 蓝光治疗 药浴 经皮胆红素 血清总胆红素 血清直接胆红素 

分 类 号：R722.17[医药卫生—儿科]