2012-2019年北京市昌平区散发腹泻病例四种病毒监测结果分析  

Analysis of the surveillance results of four viruses among sporadic cases of infectious diarrhea in Changping district of Beijing,2012-2019

作　　者：彭华[1] 李东迅[1] 李楠[1] 王维钧[1] 舒高林 田祎[2] 闻艳红[1] 徐代庆[1] 银安琪 严寒秋[2] PENG Hua;LI Dong-xun;LI Nan;WANG Wei-jun;SHU Gao-lin;TIAN Yi;WEN Yan-hong;XU Dai-qing;YIN An-qi;YAN Han-qiu(Changping District Center for Disease Prevention and Control,Beijing 102206,China;不详)

机构地区：[1]北京市昌平区疾病预防控制中心,102206 [2]北京市疾病预防控制中心/北京市预防医学研究中心/食物中毒诊断溯源技术北京市重点实验室

出　　处：《首都公共卫生》2021年第4期185-188,共4页Capital Journal of Public Health

基　　金：国家科技重大专项(编号:2018ZX10714002-003-002)。

摘　　要：目的对北京市昌平区2012-2019年散发腹泻病例4种病毒监测结果进行分析,了解其流行特征。方法采集此期间辖区2家哨点医院肠道门诊散发腹泻病例便样本960份,提取核酸后用实时荧光RT-PCR方法检测A组轮状病毒、GⅠ/GⅡ组诺如病毒、星状病毒和肠道腺病毒,用描述性流行病学方法从时间、性别和年龄分布分析其流行特征。结果960份便样本的病毒总检出率为32.29%(310/960),GⅠ/GⅡ组诺如病毒、A组轮状病毒、星状病毒和肠道腺病毒检出率分别为18.96%(182/960)、10.63%(102/960)、1.98%(19/960)和0.73%(7/960);在不同年份、性别和年龄组中,均为GⅠ/GⅡ组诺如病毒检出率最高,A组轮状病毒次之;GⅠ/GⅡ组诺如病毒春季检出率最高(28.33%,68/240),冬季次之(22.50%,54/240);A组轮状病毒冬季检出率最高(25.42%,61/240),春季次之(9.58%,23/240)。结论GⅠ/GⅡ组诺如病毒和A组轮状病毒是北京市昌平区冬春季散发腹泻病例的主要病原。Objective To understand the epidemiological characteristics of four viruses among sporadic cases of infectious diarrhea in Changping district of Beijing during 2012-2019.Methods During 2012-2019,960 fecal samples from sporadic cases of infectious diarrhea were collected in two sentinel hospitals.After nucleic acids were extracted,real-time fluorscent RT-PCR was used to detect group A rotavirus,norovirus GⅠ/GⅡ,astrovirus and enteric adenovirus.The epidemiological characteristics of four viruses were analyzed by descriptive epidemiological method in the terms of time,genders and age distribution.Results The total positive rate of four viruses was 32.29%(310/960),and the positive rate of norovirus GⅠ/GⅡ,group A rotavirus,astrovirus and enteric adenovirus were 18.96%(182/960),10.63%(102/960),1.98%(19/960)and 0.73%(7/960),respectively.The detected rate of norovirus GⅠ/GⅡin different years,genders and different age was highest followed by group A rotavirus.The detected rate of norovirus GⅠ/GⅡwas highest in spring(28.33%,68/240),followed by winter(22.50%,54/240).The detected rate of group A rotavirus was highest in winter(25.42%,61/240),followed by spring(9.58%,23/240).Conclusions Norovirus GⅠ/GⅡand group A rotavirus were the main pathogens among sporadic cases of viral diarrhea in Changping district of Beijing in spring and winter.

关 键 词：病毒性腹泻 诺如病毒 轮状病毒 星状病毒 肠道腺病毒 

分 类 号：R446.5[医药卫生—诊断学] R574[医药卫生—临床医学]