绝经前后三阴性乳腺癌超声特征的对比研究  

A comparative study of ultrasonic characteristics of triple negative breast cancer before and after menopause

作　　者：朱萍 刘俊[1] 梁喜[1] ZHU Ping;LIU Jun;LIANG Xi(Department of Ultrasound,Wuxi Maternal and Child Health Care Hospital,Jiangsu 214000,China)

机构地区：[1]江苏省无锡市妇幼保健院超声科,214000

出　　处：《临床超声医学杂志》2021年第9期711-713,共3页Journal of Clinical Ultrasound in Medicine

摘　　要：目的对比分析绝经前后三阴性乳腺癌(TNBC)的超声特征。方法选取我院经手术病理证实的TNBC患者66例,包括绝经前女性40例(绝经前组)和绝经后女性26例(绝经后组),对比分析两组超声及临床病理特征。结果两组肿瘤最大径、位置、组织学等级、Ki-67表达、腋窝淋巴结转移、肿瘤边界、微钙化、内部回声、后方回声比较差异均无统计学意义;两组肿瘤形态、生长方式、边缘、血流分级及乳腺影像报告和数据系统(BI-RADS)分类比较差异均有统计学意义(均P<0.05)。与绝经后组比较,绝经前组TNBC表现为形态规则、水平生长、边缘微分叶、血流Adler 3级及BI-RADS分类3~4类的占比更高,差异均有统计学意义(均P<0.05)。结论绝经前后TNBC声像图特征具有显著差异,超声可为临床鉴别诊断提供参考依据。Objective To compare the ultrasonic characteristics in patients with triple negative breast cancer(TNBC)before and after menopause.Methods A total of 66 patients with TNBC confirmed by surgery and pathology in our hospital were selected,including 40 premenopausal women(premenopausal group)and 26 postmenopausal women(postmenopausal group).The ultrasound and clinicopathological characteristics of the two groups were retrospectively compared.Results There were no significant difference between the two groups in tumor diameter,tumor location,histological grade,Ki-67 expression,axillary lymph node metastasis,tumor boundary,microcalcification,internal echo,and posterior echo.There were statistically significant differences between the two groups in terms of tumor morphology,growth pattern,margin,blood flow grade and BI-RADS classification(all P<0.05).Compared with the postmenopausal group,the premenopausal group showed higher proportion of regular morphology,horizontal growth,marginal differential lobes,blood flow Adler level 3,and BI-RADS classification 3~4 categories,with statistically significant differences(all P<0.05).Conclusion The ultrasonic characteristics in patients with TNBC before and after menopause are significantly different,and ultrasound could provide a reference for clinical differential diagnosis of TNBC.

关 键 词：超声检查 乳腺肿瘤 恶性 三阴性 绝经 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]