老年住院患者骨质疏松与认知障碍的相关性分析  

Correlation analysis between osteoporosis and cognitive impairment in elderly hospitalized patients

作　　者：张薇薇 张伟[1] 朱晨[2] 戴雨濛 张贤祚 黄威[2] 孙梦雯 ZHANG Weiwei;ZHANG Wei;ZHU Chen(Department of Geriatrics,the First Affiliated Hospital of USTC,Hefei 230022,China)

机构地区：[1]中国科学技术大学附属第一医院(安徽省立医院)老年医学科,安徽合肥230022 [2]中国科学技术大学附属第一医院(安徽省立医院)骨科,安徽合肥230022

出　　处：《安徽医学》2021年第9期970-973,共4页Anhui Medical Journal

基　　金：安徽省卫生健康委科研项目(项目编号:AHWJ2021b079);中国科学院战略性先导科技专项课题(项目编号:XDB39040500)。

摘　　要：目的探究老年住院患者骨质疏松与认知障碍的相关性。方法回顾性分析2018年1月至2021年3月中国科学技术大学附属第一医院老年医学科收治的38例老年患者临床资料,依据是否患有骨质疏松分组,将其中17例骨质疏松患者设为观察组,21例无骨质疏松患者设为对照组进行比较。采用logistic回归模型分析性别、教育程度以及认知障碍对患者骨质疏松的影响,采用Pearson相关分析检验简易精神状态检查(MMSE)评分与骨密度(BMD)的关联性。结果多因素logistic回归分析显示,认知障碍是老年住院患者发生骨质疏松的危险因素(OR=6.910,95%CI:1.358~35.166,P=0.020),MMSE评分与患者腰椎骨密度T值(r=0.497,P=0.002)及髋关节骨密度T值(r=0.367,P=0.024)均存在线性相关关系。结论认知障碍可能是老年住院患者患骨质疏松的风险因素之一,应当引起医务工作者及老年患者家属的重视。Objective To explore the correlation between cognitive impairment and osteoporosis in elderly hospitalized patients.Methods A retrospective analysis was conducted in 38 elderly in-patients who were admitted to the Department of Geriatrics,theFirst Affiliated Hospital of University of Science and Technology of China from January 2018 to March 2021.They were divided into the observation group(n=17)and the control group(n=21)based on osteoporosis diagnosis.A logistic regression model was used to analyze the correlation between the patients’gender,education level,cognitive impairment and osteoporosis.A Pearson’s correlation model was used to verify the linear correlation between the mini-mental state examination(MMSE)score and bone mineral density(Bone Mineral Density,BMD).Results The multivariable logistic regression showed that cognitive impairment might be a possible risk factor for osteoporosis in hospitalized elderly patients(OR=6.910,95%CI:1.358~35.166,P=0.020).There was a linear correlation between the MMSE score and the patients’lumbar spine bone mineral density T value(r=0.497,P=0.002)and hip joint bone mineral density T value(r=0.367,P=0.024).Conclusions Cognitive impairment may be one of the risk factors for osteoporosis in elderly hospitalized patients,and it should be paid attention to by medical workers and their families.

关 键 词：认知障碍 骨质疏松 骨密度 相关性分析 

分 类 号：R580[医药卫生—内分泌] R749.1[医药卫生—内科学]