解毒降糖复瘫汤治疗糖尿病性脑梗死急性期患者60例  

Clinical effect of Jiedu Jiangtang Futan decoction in treatment of patients in the acute stage of diabetic cerebral infarction: an analysis of 60 cases

作　　者：胡穗发[1] 胡小风[1] 石浩珂 谢桂[1] 周成[1] 熊佳[1] 廖小香[1] 彭天忠[1] HU Suifa;HU Xiaofeng;SHI Haoke;XIE Gui;ZHOU Cheng;XIONG Jia;LIAO Xiaoxiang;PENG Tianzhong(Hongdu Hospital of Traditional Chinese Medicine,Nanchang 330008,Jiangxi,China;Jiangxi University of Traditional Chinese Medicine,Nanchang 330045,Jiangxi,China)

机构地区：[1]南昌市洪都中医院,江西南昌330008 [2]江西中医药大学,江西南昌330045

出　　处：《湖南中医杂志》2021年第8期1-4,共4页Hunan Journal of Traditional Chinese Medicine

基　　金：江西省卫生健康委员会中医药科技计划项目(2017A167)。

摘　　要：目的:观察解毒降糖复瘫汤治疗糖尿病性脑梗死(DCI)急性期患者的临床疗效。方法:将120例DCI急性期患者随机分为治疗组和对照组,每组各60例。2组均给予基础治疗,治疗组予以解毒降糖复瘫汤治疗,对照组予以补阳还五汤加减治疗。2组均采用脑卒中残损评定法(SIAS)、Barthel指数(BI)、汉密尔顿抑郁量表(HRSD)和简明精神状态检查表(MMSE)进行评价,并比较疗效。结果:总有效率治疗组为90.00%(54/60),对照组为80.00%(48/60),2组比较,差异有统计学意义(P<0.05);2组患者治疗后SIAS、BI、MMSE评分均有改善,且治疗组优于对照组(P<0.05),而2组HRSD评分比较,差异无统计学意义(P>0.05)。结论:解毒降糖复瘫汤治疗DCI急性期患者疗效确切,能明显改善患者神经功能和日常生活能力,值得临床推广应用。Objective: To investigate the clinical effect of Jiedu Jiangtang Futan decoction in the treatment of patients in the acute stage of diabetic cerebral infarction(DCI).Methods: A total of 120 patients in the acute stage of DCI were randomly divided into treatment group and control group, with 60 patients in each group.In addition to basic treatment, the patients in the treatment group were given Jiedu Jiangtang Futan decoction, and those in the control group were given Buyang Huanwu decoction.The two groups were evaluated based on Stroke Impairment Assessment Set(SIAS),Barthel Index(BI),Hamilton Rating Scale for Depression(HRSD),and Mini-Mental State Examination(MMSE),and clinical outcome was compared between the two groups.Results: There was a significant difference in overall response rate between the treatment group and the control group [90.00%(54/60) vs 80.00%(48/60),P<0.05].After treatment, both groups had significant improvements in SIAS,BI,and MMSE scores, and the treatment group had significantly better scores than the control group(P<0.05);there was no significant difference in HRSD score between the two groups(P>0.05).Conclusion: Jiedu Jiangtang Futan decoction has a marked clinical effect in the treatment of patients in the acute stage of DCI and can significantly improve patients’ neurological function and activities of daily living, and therefore, it holds promise for clinical application.

关 键 词：糖尿病性脑梗死 急性期 中医药疗法 解毒降糖复瘫汤 补阳还五汤 

分 类 号：R259.871[医药卫生—中西医结合] R277.733.3[医药卫生—中医内科学]