患者临床结局报告量表译评、建构及中医临床实践优化模式探讨  

Study on Translation,Evaluation and Development of PRO Scales Involving Optimized Model of TCM Clinical Practice

作　　者：曾令烽[1,2,3] 杨伟毅 梁桂洪[1,2] 肖萧 罗明辉 陈红云[1] 潘建科[1] 赵金龙[2] 赵第 黄和涛 韩燕鸿 欧爱华[1] 梁伟雄[1] 刘军[1,2,3] Zeng Lingfeng;Yang Weiyi;Liang Guihong;Xiao Xiao;Luo Minghui;Chen Hongyun;Pan Jianke;Zhao Jinlong;Zhao Di;Huang Hetao;Han Yanhong;Ou Aihua;Liang Weixiong;Liu Jun(Guangdong Provincial Hospital of Chinese Medicine,The Second Affiliated Hospital,Guangzhou University of Chinese Medicine,Guangzhou 510120,China;The Second Clinical Medical College of Guangzhou University of Chinese Medicine/Post-doctoral Research Station,Guangzhou 510405,China;Bone and Joint Research Team of Degeneration and Injury,Guangdong Provincial Academy of Chinese Medical Sciences,Guangzhou 510120,China)

机构地区：[1]广东省中医院/广州中医药大学第二附属医院,广州510120 [2]广州中医药大学第二临床医学院/博士后科研流动站,广州510405 [3]广东省中医药科学院骨与关节退变及损伤研究团队,广州510120

出　　处：《世界科学技术-中医药现代化》2021年第6期2092-2099,共8页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：广东省卫健委广东省医学科学技术研究基金项目(B2019091):全膝关节置换TKA术前及术后测定量表N-KSS 2.0的引进与考核,负责人:曾令烽;国家自然科学基金委员会青年项目(82004383):基于HSP90调控Hippo-YAP信号通路诱导自噬促进BMSCs成骨分化探讨补肾中药干预骨质疏松的作用机制;负责人:曾令烽;广东省中医院中医药科学技术研究专项(YN2019ML08):基于岭南瘀湿合治理论探讨膝骨关节炎临床诊治及慢病管理研究,负责人:刘军。

摘　　要：患者临床结局报告(PRO)侧重于近代心理学概念和策略,对目标受试者的主观体验、本体症状改善情况、以及疾患诊治满意程度予以综合评价;这过程所体现的"以人为本"思维与传统中医经典理论相吻合,故PRO在传统医学研究中日趋受到关注,是当前中医临证与效应评析至为关键的内容之一。本文围绕上述核心问题在PRO的定义及溯源、PRO的测评要点和价值、PRO量表的评译和泛文化编制、中医临床效应测评及PRO量表的应用、PRO量表的建构及中医临床实践模式优化等方面展开论述,并就PRO国外量表的引进及特性考评、中医PRO量表研制及评价等方面进行相关分析,以期为当前中医特色PRO量表研制及临床实践提供参考。The patient reported outcome(PRO)aims to evaluate the subjective experience of subjects,the improvement of subjects’symptoms,the satisfaction degree of diagnosis and treatment of diseases,using the theory and strategies of modern psychology.During this process,people-oriented concept has been observed,which was consistent with the classical theory of traditional Chinese medicine(TCM).PRO has attracted increasing attention in TCM medical research,as well as being chosen as one of the key contents of current TCM clinical evidence and effect evaluation.Based on the core problem and principles,this paper attempted to discuss the issues such as the definition and sources of PRO,the measurement and meanings of PRO,interpretation and cross-cultural compilation of scales,application of PRO in TCM clinical effect assessment,construction of PRO and its model optimization in TCM clinical practice,etc.,focusing on the introduction and evaluation of PRO scale abroad,the establishment and evaluation of TCM PRO scale,and so on.We hope that all these considerations can provide reference for better understanding of the development of PRO scale and TCM clinical practice.

关 键 词：临床结局评价 量表译评 量表建构 中医临床实践 模式探讨 

分 类 号：R2-031[医药卫生—中西医结合]