一种氧化石墨烯血栓去除盾构针及其制备  

Removal of Shield Needles from Graphene Oxide Thrombus and Preparation

作　　者：杨玉婷 钟远坚 赵立春[1] 宋元博 于丽 YANG Yuting;ZHONG Yuanjian;ZHAO Lichun;SONG Yuanbo;YU Li(Guangxi University of Chinese Medicine,Nanning,530200)

机构地区：[1]广西中医药大学,南宁市530200

出　　处：《中国医疗器械杂志》2021年第5期492-496,共5页Chinese Journal of Medical Instrumentation

摘　　要：动脉粥样硬化是临床常见的慢性炎症性疾病.其会导致血管内膜增厚.管腔狭窄闭塞和血栓形成,从而引发心绞痛、高血压、心肌梗死等疾病.对人类的生命健康造成严重威胁。该研究提供了一种氧化石墨烯血栓去除盾构针及其制备方法。该氧化石墨烯盾构针主要包括柔性转轴、辐射状柔性杆.自转针头.吸附总管和施药总管.激光测量器.高清摄像头等结构,具有以下优点:一是实现多角度旋磨血栓.旋磨精准.避免血管破损感染;二是能实现在旋磨过程中施加溶栓药物及吸附小块血栓.有效避免血管二次栓塞;三是在自转针头涂覆了氧化石墨烯涂层.能够避免细菌侵入.防止感染。该研究对于血栓治疗的发展.推动石墨烯在医疗领域的应用具有实际参考价值。Atherosclerosis is a chronic inflammatory disease commonly seen in clinical practice.It can lead to thickening of vascular intima,occlusion of lumen stenosis and thrombosis,leading to angina pectoris,hypertension,myocardial infarction and other diseases,posing a serious threat to human life and health.This study provides a method for removing shield needles from graphene oxide thrombus and its preparation.The graphene oxide shield needle mainly includes flexible rotating shaft,radial flexible rod,rotating needle,adsorption main pipe and dosing main pipe,laser measuring device,high definition camera and other structures,which has the following advantages:firstly,it achieves multi-angle rotation grinding thrombosis,precise rotation grinding,avoids vascular damage and infection;secondly,thrombolytic drugs can be applied in the process of rotary grinding and small thrombus can be adsorbed to effectively avoid secondary embolization of blood vessels;thirdly,it a coating of graphene oxide on a rotating needle,which protects against bacteria and infection.This study has practical reference value for the development of thrombotherapy and the application of graphene in the medical field.

关 键 词：血栓 氧化石墨烯 动脉粥样硬化 机械取栓 

分 类 号：TH77[机械工程—仪器科学与技术]