不同浓度胆红素对新生儿肾脏的影响  

Effects of different concentrations of bilirubin on neonatal kidney

作　　者：王惠颖 苏敏[1] 高翔羽[1] Wang Huiying;Su Min;Gao Xiangyu(Department of Neonatology,Xuzhou Central Hospital(Xuzhou School of Clinical Medicine of Nanjing Medical University),Xuzhou 221009,Jiangsu Province,China;Department of Pediatrics,Hangzhou Hospital of Traditional Chinese Medicine,Hangzhou 311000,China)

机构地区：[1]徐州市中心医院(南京医科大学徐州临床医学院)新生儿科,江苏徐州221009 [2]杭州市中医院儿科,311000

出　　处：《中华实用儿科临床杂志》2021年第17期1357-1360,共4页Chinese Journal of Applied Clinical Pediatrics

基　　金：江苏省青年医学人才(QNRC2016384)。

摘　　要：高胆红素血症是新生儿最常见且需要评估和治疗的临床症状,高浓度的游离未结合胆红素已经被证实对神经组织有直接毒性并损害其功能,但对神经外器官或系统(如肾脏、心脏、肝脏、肠道、肺脏、凝血及免疫功能等)的影响尚存在较大争议。为了解不同浓度胆红素对新生儿肾脏的影响,现对近年来相关研究作一综述。Hyperbilirubinemia is the most common clinical symptom in neonates that requires evaluation and treatment.It has been confirmed that free indirect bilirubin of high concentration have direct toxic effect on nerve tissue and impair its function,but its effect on extraneural organs or systems(such as kidney,heart,liver,intestine,lung,blood coagulation and immune function)is still controversial.This present study reviewed the previous relevant research in recent years to understand the effect of bilirubin of different concentrations on neonatal kidney.

关 键 词：高胆红素血症 肾脏 婴儿 新生 

分 类 号：R722.1[医药卫生—儿科]