探讨老年糖尿病患者临床检验尿白蛋白、免疫球蛋白G及β_(2)微球蛋白临床分析  

Exploring the Clinical Analysis of Urine Albumin, Immunoglobulin G and β_(2) Microglobulin in Elderly Diabetic Patients

作　　者：林道烺 陈洁琼[1] 王巧兰[1] LIN Daolang;CHEN Jieqiong;WANG Qiaolan(DeparSment of Laboratory Medicine,Fujian Provincial Government Hospital,Fuzhou,Fujian Province,350002 China)

机构地区：[1]福建省级机关医院检验科,福建福州350002

出　　处：《糖尿病新世界》2021年第15期57-60,共4页Diabetes New World Magazine

摘　　要：目的对老年糖尿病患者的尿白蛋白、免疫球蛋白G以及β_(2)微球蛋白临床检验的结果进行分析,并探讨其诊断应用价值。方法选取2018年11月-2020年11月间收治的老年糖尿病患者500例作为研究对象,将其设为研究组,并以同期收治的健康志愿者500名作为对照组,分别对两组受检者的尿白蛋白、免疫球蛋白G以及β_(2)微球蛋白的水平以及阳性率进行测定、计算和比较。同时,按照老年糖尿病患者病情的严重程度对其进行组内再分组,分为单纯糖尿病组(309例)和糖尿病肾病组(191例),比较小组内患者的尿白蛋白、免疫球蛋白G、β_(2)微球蛋白水平、阳性率。结果研究组老年糖尿病组患者的尿白蛋白、免疫球蛋白G、β_(2)微球蛋白测定值、检验阳性率均显著高于对照组,比较差异有统计学意义(P<0.05)。对老年糖尿病患者进行再分组后,糖尿病肾病组患者的尿白蛋白、免疫球蛋白G、β2微球蛋白测定值、检验阳性率均显著高于单纯糖尿病组患者,比较差异有统计学意义(P<0.05)。结论通过对尿白蛋白、免疫球蛋白G、β_(2)微球蛋白等指标进行临床检验,并对其进行定量和定性分析,可以为老年糖尿病患者的诊断、病情严重程度的判断以及早期治疗提供可靠指导,值得临床推广应用。Objective To analyze the clinical test results of urine albumin,immunoglobulin G and β_(2) microglobulin in elderly diabetic patients,and to explore their diagnostic value.Methods 500 elderly diabetic patients who were admitted between November 2018 and November 2020 were selected as the research objects.They were set as the study group,and500 healthy volunteers admitted during the same period were used as controls.The levels of urine albumin,immunoglobulin G and β_(2) microglobulin and the positive rate were measured,calculated and compared.At the same time,the elderly diabetic patients were regrouped according to the severity of their condition,and divided into simple diabetes group(309cases)and diabetic nephropathy group(191 cases).Compared the urine albumin,immunoglobulin G,and immunoglobulin G and β_(2) microglobulin level and positive rate of the patients in the group.Results The measured values of urine albumin,immunoglobulin G,β_(2) microglobulin and the positive rate of the study group of elderly diabetic patients were significantly higher than those of the control group.The difference was statistically significant(P<0.05).After the elderly diabetic patients were regrouped,the urine albumin,immunoglobulin G,β_(2) microglobulin measured values and the test positive rate of the diabetic nephropathy group were significantly higher than those of the simple diabetic group,and the difference was statistically significant(P<0.05).Conclusion Through clinical testing of urine albumin,immunoglobulin G,β_(2) microglobulin and other indicators,and quantitative and qualitative analysis of them,it can provide reliable guidance for the diagnosis of elderly diabetic patients,the judgment of the severity of the disease,and early treatment,which is worthy of clinical application.

关 键 词：老年糖尿病 尿白蛋白 免疫球蛋白G β_(2)微球蛋白 临床检验 

分 类 号：R587.1[医药卫生—内分泌] R446.1[医药卫生—内科学]