抗疫良方麻杏石甘汤研究热点、发展趋势与前沿分析——基于CiteSpace的知识图谱分析  

Research Hotspots, Development Trends and Frontal Analysis on Maxing Shigan Decoction Against Epidemic-Knowledge Map Analysis Based on Cite Space

作　　者：王朝 尹梦碟 郑培永[3] 邓宏勇[1] 许吉[1] 张洋[1] 袁敏[1] Wang Chao;Yin Mengdie;Zheng Peiyong;Deng Hongyong;Xu Ji;Zhang Yang;Yuan Min(Collaborative Innovation Center of Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China;The Fifth Clinical Medical College of Guangzhou University of Chinese Medicine,Guangzhou 510095,China;Longhua Hospital,Shanghai University of Traditional Chinese Medicine,Shanghai 201203,China)

机构地区：[1]上海中医药大学协同创新中心,上海201203 [2]广州中医药大学第五临床医学院,广州510095 [3]上海中医药大学附属龙华医院,上海201203

出　　处：《世界科学技术-中医药现代化》2021年第5期1546-1554,共9页Modernization of Traditional Chinese Medicine and Materia Medica-World Science and Technology

基　　金：国家科学技术部国家“十三五”传染病重大专项课题(2017ZX10305501-002):流行性出血热等发热伴出血证候群方向中西医结合治疗方案研究,负责人:郑培永;国家科学技术部国家重点研发计划"中医药现代化研究"重点专项2019年度项目(2019YFC1709803):基于人工智能大数据的中医药数据分析自动化及可视化呈现研究,负责人:邓宏勇。

摘　　要：目的通过数据挖掘分析近20年麻杏石甘汤相关文献,把握该领域的研究热点并展望研究趋势。方法运用CiteSpace软件对近20年中国知网(CNKI)中麻杏石甘汤相关文献的年发文量、作者、机构和总体上呈现波动增长趋势;有201位作者被纳入,发文量≥10篇的有6人,形成了以徐国良教授为主和以卢芳国教授为中心的两大的团队;共纳入41个研究机构,其中湖南中医药大学发文35篇,北京中医药大学发文26篇,江西中医药大学发文22篇,为该领域的三大主要研究机构;图谱中共纳入237个关键词,有32个高动物实验、组方研究以及药理研究等;主要病种包含不同类型呼吸道传染病以及小儿肺炎、社区获得性肺炎、慢性阻塞性肺疾病、支气管哮喘等,治疗方法上多采用中西医结合疗法,或是联用其他方药、穴位贴敷等;近年来倾向于麻杏石甘汤在临床上的研究,从支气管炎、甲型流感到新冠肺炎均有涉及;药物机理上看,麻杏石甘汤与"炎症因子""、炎症风暴"的相关研究是十分热门的研究方向,具有较高学术潜力;对麻杏石甘汤的研究形成了稳定的学术团队,但尚未形成核心研究团队,且研究团队、研究机构之间合作较少。Objective To grasp the research highlights and the trends in the study of Maxin Shigan Decoction through data mining on the related literatures over the past two decades. Methods Use CiteSpace to do an visualization analysis on annual paper publishing, authors, institutions and keywords in related literatures of Maxing Shigan Decoction over the past two decades in CNKI and draw a knowledge map. Results After screening, a total of 1490 articles were included,with an average annual volume of approximately 75 articles, which showed an overall volatile growth trend;201 authors were included, 6 with a volume of ≥ 10 articles, forming two major teams with Professor Xu Guoliang and Professor Lu Fangguo as the centers;41 research institutes have been included, among which there are three major research institutions, namely, Hunan University of Traditional Chinese Medicine that published 35 papers, Beijing University of Traditional Chinese Medicine26 papers, and Jiangxi University of Traditional Chinese Medicine 22 papers;237 key words have been included inknowledge map, with 32 of high betweenness centrality, 14 rational clusterings and 25 sudden words. Conclusion The researches of Maxing Shigan Decoction involve clinical research, animal experiments,prescription research and pharmacological research etc.;the target diseases mainly include pediatric pneumonia,community-acquired pneumonia, chronic obstructive pulmonary disease, bronchial asthma, influenza and different Types of respiratory tract infectious diseases;the treatment methods are mostly integrated traditional Chinese and Western medicine, or treatments combined with other prescriptions or acupoint application, etc. In recent years, the research hotspots have tended to clinical research, focusing on clinical efficacy. In recent years, novel coronavirus pneumonia has been a hot topic in clinical research. It is involved in bronchitis, influenza A and neon coronitis. In terms of drug mechanism, the research of Maxing Shigan Decoction and inflammatory factors and

关 键 词：麻杏石甘汤 CITESPACE 知识图谱 可视化分析 新冠肺炎 

分 类 号：R2-031[医药卫生—中西医结合]