从“肾脑相关”分析维持性血液透析患者认知功能障碍的中西医研究进展  

Study Progress of Integrated Chinese and Western Medicine on Cognitive Impairment in Maintenance Hemodialysis Patients Based on“Correlation between Kidney and Brain”

作　　者：竺佳怡 陈敏[1] ZHU Jiayi;CHEN Min(Yueyang Hospital of Integrated Traditional Chinese and Western Medicine,Shanghai University of Traditional Chinese Medicine,Shanghai 200437,China)

机构地区：[1]上海中医药大学附属岳阳中西医结合医院,上海200437

出　　处：《山东中医杂志》2021年第10期1153-1158,共6页Shandong Journal of Traditional Chinese Medicine

基　　金：上海市浦江人才计划项目(编号:18PJD049)。

摘　　要：维持性血液透析(MHD)患者往往会出现记忆力下降、执行功能减退、注意力不集中等多认知领域联合受损的表现。由于其发病机制尚未明确,现代医学尚未有改善MHD患者认知功能障碍的标准治疗方案。中医学在“肾脑相关”学说的指导下,结合“肾精生髓,脑为髓海”和“经脉络属,肾脑相连”的理论,通过中药及针灸治疗,凭借多靶点调控的特点在改善患者预后等方面发挥其优势。故而,整合中西医两方面的相关理论研究,可为防治MHD患者认知障碍提供更合理的干预措施,从而进一步提高MHD患者的生活质量。参考文献48篇。Maintenance hemodialysis(MHD)patients always suffer from multiple cognitive domain impairment such as memory decline,decreased executive function and inattentiveness.Since the pathogenesis is unclear,there is no standard therapy to relieve the cognitive impairment of MHD patients in western medicine.Based on the theory of“correlation between kidney and brain”,in combination with the theory of“kidney essence generating marrow,and brain is the marrow sea”and the theory“kidney connects brain through meridians and collaterals”,traditional Chinese medicine(TCM)could take advantage of the multi-target regulation to improve prognoses of patients through Chinese medicinals,acupuncture and moxibustion.Therefore,through combining relevant theoretical research in both TCM and western medicine,a more reasonable intervention could be provided for the prevention and treatment of cognitive impairment in MHD patients,so as to improve quality of life.There are 48 research papers cited in the references.

关 键 词：维持性 血液透析 终末期肾病 认知功能障碍 脑主神明 肾脑相关 

分 类 号：R692.5[医药卫生—泌尿科学] R277.7[医药卫生—外科学]