应用肾衰康方对慢性肾衰竭患者血清微炎症状态的影响及肾功能保护作用的提升研究  

Study on the effect of Shenshuaikang decoction on serum microinflammatory state and renal function protection in patients with chronic renal failure

作　　者：罗丽 郑剑琴 LUO Li;ZHENG Jianqin(Department of Nephrology,Clifford Hospital,Guangdong,Guangzhou 511495,China)

机构地区：[1]广东祈福医院肾内科,广州511495

出　　处：《广州医药》2021年第5期97-100,共4页Guangzhou Medical Journal

基　　金：广东省中医药局科研项目(20202149)。

摘　　要：目的分析慢性肾衰竭患者接受肾衰康方治疗对其血清微炎症状态的影响及肾功能的保护作用。方法将2020年1月—2020年12月作为研究时间段,选取期间广东祈福医院接诊的50例慢性肾衰竭患者,另将随机数字表法作为分组依据,将全部病例分为对照组(行常规治疗,纳入25例)、观察组(加用肾衰康方治疗,纳入25例),对组间中医症状评分、血清微炎症状态、肾功能指标、氧化应激指标展开分析。结果组间中医症状评分、血清微炎症状态、肾功能指标、氧化应激指标在治疗前无明显差异,P>0.05;观察组中医症状评分、血清微炎症状态、肾功能指标、氧化应激指标在治疗后优于对照组,P<0.05。结论肾衰康方对改善慢性肾衰竭患者血清微炎症状态、氧化应激水平、临床症状均有较好效果,且能保护肾功能,值得推广。Objective To analyze the effect of Shenshuaikang decoction on serum microinflammation and renal function in patients with chronic renal failure.Methods From January 2020 to December 2020,50 patients with chronic renal failure treated by Clifford Hospital were selected,and the random number table method was used for grouping.All cases were divided into control group(n=25)and observation group(n=25).The TCM symptom score,serum microinflammatory state,renal function index and oxidative stress index were analyzed.Results There were no significant differences in TCM symptom score,serum microinflammatory state,renal function index and oxidative stress index between the two groups before treatment,P>0.05;the TCM symptom score,serum microinflammatory state,renal function index and oxidative stress index of the observation group were better than those of the control group after treatment,P<0.05.Conclusion Shenshuaikang decoction has good effect on improving serum microinflammation,oxidative stress level and clinical symptoms of patients with chronic renal failure,and also can protect renal function,which is worthy of promotion.

关 键 词：肾衰康方 慢性肾衰竭 血清微炎症状态 肾功能 保护作用 

分 类 号：R692.5[医药卫生—泌尿科学]