萎缩性光老化:光老化的一种新亚型  

Atrophic photoaging: a new subtype of photoaging

作　　者：郑慧颖 葛一平 宗文凯 林彤 ZHENG Huiying;GE Yiping;ZONG Wenkai;LIN Tong(Institute of Dermatology and Hospital of Skin Diseases,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing 210000,China)

机构地区：[1]中国医学科学院北京协和医学院皮肤病医院,南京210000

出　　处：《中国麻风皮肤病杂志》2021年第12期805-808,共4页China Journal of Leprosy and Skin Diseases

基　　金：江苏省重点研发计划(社会发展)面上项目(编号:BE2017808);中国医学科学院医学与健康科技创新项目(编号:CIFMS-2017-I2M-1-017)。

摘　　要：光老化的表现在个体之间差异较大,根据其表现特点可进一步细分为萎缩性光老化和肥厚性光老化。形成不同光老化亚型的机制尚不明确,其中萎缩性光老化可能与MC1R基因多态性相关。萎缩性光老化与皮肤肿瘤及皮肤癌前病变存在相关性,在筛查潜在皮肤癌前病变的基础上,应从多个方面积极开展治疗。本文就萎缩性光老化的临床表现、与皮肤肿瘤的关联、影响因素及其评价工具及防治方法进行综述。Clinical manifestations of photoaging vary widely among individuals.It can be further divided into two subtypes according to their characteristics:atrophic photoaging and hypertrophic photoaging.Though mechanisms underlying different subtypes remains to be elucidated,atrophic photoaging may be related to MC1R gene polymorphisms and has close relationship with skin cancer and precancerous changes.Multiple measures should be taken to treat atrophic photoaging on the basis of screening potential skin cancerous changes.This paper reviews the clinical manifestations of atrophic photoaging,association with skin tumor,influencing factors,assessment tools and treatment methods.

关 键 词：光老化 萎缩性 肥厚性 

分 类 号：R751[医药卫生—皮肤病学与性病学]