CRRT在感染性休克致急性肾功能衰竭治疗中的效果评价  

Effect evaluation of CRRT in the treatment of acute renal failure caused by septic shock

作　　者：许进雄 XU Jin-xiong(Shanwei People’s Hospital,Shanwei 516600,China)

机构地区：[1]汕尾市人民医院,516600

出　　处：《中国实用医药》2021年第27期45-47,共3页China Practical Medicine

摘　　要：目的探究连续性肾脏替代治疗(CRRT)在感染性休克致急性肾功能衰竭治疗中的效果。方法42例感染性休克致急性肾功能衰竭患者作为研究对象,随机分为观察组和对照组,各21例。对照组患者选择常规治疗措施,观察组患者在常规治疗基础上选择CRRT进行治疗。比较两组患者治疗前后血液生化指标以及病死率。结果治疗后,观察组患者血肌酐(104.4±27.4)μmol/L、尿素氮(8.5±1.3)mmol/L、二氧化碳结合力(22.5±2.3)mmol/L均优于对照组的(136.4±34.7)μmol/L、(16.2±2.5)mmol/L、(19.6±2.7)mmol/L,差异均具有统计学意义(P<0.05)。观察组患者中4例(19.05%)经过疾病急性期,2例(9.52%)需要进行血液透析治疗,4例(19.05%)肾功能恢复,3例(14.29%)急性期死亡。对照组患者中6例(28.57%)经过疾病急性期,4例(19.05%)需要进行血液透析治疗,6例(28.57%)肾功能恢复,9例(42.86%)急性期死亡。观察组急性期死亡率14.29%低于对照组的42.86%,差异具有统计学意义(P<0.05)。结论针对感染性休克致急性肾功能衰竭患者,选择CRRT进行治疗能显著提升救治率,值得临床应用和借鉴。Objective To investigate the effect of continuous renal replace treatment(CRRT)in the treatment of acute renal failure caused by septic shock.Methods A total of 42 patients with acute renal failure caused by septic shock were studied and randomly divided into observation and control groups,with 21 cases in each group.Patients in the control group received conventional therapy,and patients in the observation group received CRRT based on the conventional therapy.The blood biochemical indexes and mortality of the two groups before and after treatment were compared.Results After treatment,the blood creatinine(104.4±27.4)μmol/L,urea nitrogen(8.5±1.3)mmol/L,and carbon dioxide binding capacity(22.5±2.3)mmol/L in the observation group were better than(136.4±34.7)μmol/L,(16.2±2.5)mmol/L,(19.6±2.7)mmol/L in the control group,and all differences were statistically significant(P<0.05).In the observation group,4 cases(19.05%)went through the acute phase of the disease,of which 2 cases(9.52%)required hemodialysis treatment,4 cases(19.05%)recovered renal function,and 3 cases(14.29%)died in the acute phase.In the control group,6 cases(28.57%)went through the acute phase of the disease,of which 4 cases(19.05%)required hemodialysis treatment,6 cases(28.57%)recovered renal function,and 9 cases(42.86%)died in the acute phase.The acute mortality rate 14.29%in the observation group was lower than 42.86%in the control group,and the difference was statistically significant(P<0.05).Conclusion For patients with acute renal failure caused by septic shock,CRRT can significantly improve the treatment rate,which is worthy of clinical application and reference.

关 键 词：连续性肾脏替代治疗 感染性休克 急性肾功能衰竭 血液生化指标 

分 类 号：R692.5[医药卫生—泌尿科学] R459.7[医药卫生—外科学]