全膝关节置换术治疗高原地区终末期膝关节大骨节病的疗效观察  

Observation of Curative Effect of Total Knee Arthroplasty on End-stage Kashin-Beck Disease in Plateau Area

作　　者：王文康[1] 郑伟坤[1] 索那旺堆 汤俊芬[1] 王新亮[1] WANG Wen-kang;ZHENG Wei-kun;Suonawangdui;TANG Jun-fen;WANG Xin-liang(Guangzhou First People's Hospital,Guangdong Guangzhou 510180;Bomi County People's Hospital,Tibet Linzhi 860300)

机构地区：[1]广州市第一人民医院,广东广州510180 [2]波密县人民医院,西藏波密860300

出　　处：《深圳中西医结合杂志》2021年第14期95-97,共3页Shenzhen Journal of Integrated Traditional Chinese and Western Medicine

基　　金：广州市医药卫生科技项目资助课题(20161A011004)。

摘　　要：目的:探讨全膝关节置换术(TKA)治疗高原地区终末期膝关节大骨节病的临床价值。方法:选取2019年6月至2019年12月于波密县人民医院治疗的25例终末期膝关节大骨节病患者为研究对象,根据治疗方式不同分为两组:置换组12例,行TKA,保守组13例,行保守治疗,比较两组患者治疗前后膝关节功能美国特种外科医院(HSS)评分和生活质量评分量表(SF–36)评分。结果:置换组患者术后开始负重时间与完全负重时间均短于保守组,差异具有统计学意义(P<0.05)。置换组患者术后6个月HSS评分、SF–36评分均高于保守组,差异具有统计学意义(P<0.05)。置换组患者术后6个月HSS优良率为83.3%,显著高于保守组的7.7%,差异具有统计学意义(P<0.05),两组均未见肺栓塞、感染等并发症。结论:TKA治疗高原地区终末期膝关节大骨节病安全有效,能明显改善患者膝关节功能和生活质量。Objective To explore the value of total knee arthroplasty (TKA) in treating end-stage Kashin-Beck disease in plateau area.Methods Twenty-five patients with end-stage Kashin-Beck disease knee arthritis in Bomi area of Tibet were observed.They were divided into two groups according to the treatment methods:12 cases in the replacement group,who underwent total knee arthroplasty in the hospital;13 cases in the conservative group,accepting conservative treatment.The knee function score (HSS) and daily life quality score (SF-36) of the two groups of patients before and after the treatment were compared.Results The weight-bearing time and complete weight-bearing time in the replacement group were shorter than those in the conservative group (P<0.05).The HSS score and SF-36 score in the replacement group were significantly higher than those in the conservative group6 months after operation (P<0.05).The excellent and good rate of HSS 6 months after operation in the replacement group was 83.3%,which was significantly higher than 7.7% in the conservative group (P<0.05).There were no complications such as pulmonary embolism and infection in both groups.Conclusion Total knee arthroplasty is safe and effective for end-stage Kashin-Beckdisease in plateau areas,which can be performed to significantly improve the knee function and quality of life of the patients.

关 键 词：大骨节病 膝关节炎 高原地区 全膝关节置换术 

分 类 号：R687.4[医药卫生—骨科学]