甲型H1N1流感病毒性肺炎患者的临床特征分析  

Analysis of clinical features of influenza A virus in patients with viral pneumonia

作　　者：何凌[1] 鲁玉婷 李耀军[1] HE Ling;LU Yu-ting;LI Yao-jun(Respiratory and Critical Care Medicine,Luohe Central Hospital,Luohe,Henan 462000,China;不详)

机构地区：[1]漯河市中心医院呼吸与危重症医学科,河南漯河462000 [2]漯河市中医院内二科,河南漯河462000

出　　处：《医药论坛杂志》2021年第9期97-99,共3页Journal of Medical Forum

摘　　要：目的对比分析甲型H1N1流感病毒肺炎的流行病学、症状、辅助检查特征,为准确的诊断和评估病情提供依据。方法将2018年10月至2020年3月于漯河市中心医院住院的240例甲型流感H1N1病毒性肺炎患者纳入研究。根据病情严重程度分为重症组及非重症组,入院后采集患者病史、流行病学和临床资料,完善血常规、C反应蛋白(CRP)等各项实验室检查及胸部CT检查。对比两组间临床特征和辅助检查结果差异。结果一般资料对比:240例患者中,男女性别比为3.8∶1。平均年龄(42.29±14.13)岁。其中非重型患者170例,重型患者7例。临床症状:首发症状以发热(79.2%)、咳嗽(45.8%)、乏力(12.5%)为主。患病后平均发热时间(8.19±4.33)d。两组间对比:重症组白细胞数(3.51±1.08)×10^(9)/L,相较于非重症组[(5.73±1.88)×10^(9)/L]明显降低(P<0.05)、重症组淋巴细胞数(0.70±0.16)×10^(9)/L,相较于非重症组[(3.51±1.08)×10^(9)/L]明显降低(P<0.05),重症组C反应蛋白(53.32±31.69)mg/L水平,较非重症组[(16.97±21.46)mg/L]明显升高。两组间最高体温:重症组平均最高体温(38.6±0.42)℃明显高于非重症组(37.9±0.59)℃,胸部CT:非重症组患者仅64.7%存在多肺叶受累。重症组患者100%为多肺叶受累。而发热天数、退热天数、总病程在两组间无明显差异(P>0.05)。结论漯河市甲流病毒性肺炎以发热、咳嗽、乏力为主要症状,重症组淋巴细胞数及白细胞数明显降低,最高体温、CRP明显升高、胸部CT多肺叶受累提示病情较重。Objective To compare and analyze the epidemiology,symptoms,and auxiliary examination characteristics of H1 N1 influenza virus pneumonia,so as to provide a basis for accurate diagnosis and evaluation of the disease.Methods Totally 240 patients with influenza A H1 N1 viral pneumonia hospitalized in our hospital from October 17,2018 to March,2020 were included in the study.According to the severity of the disease,were divided into severe group and non-serious group.After admission,the patient’s medical history,epidemiology and clinical data are collected to improve blood routine,C-reactive protein(CRP)and other laboratory tests and chest CT examination.The clinical features and the results of auxiliary examinations were compared between the two groups.Results Comparison of general data:Among the 240 patients,the male to female sex ratio was 3.8∶1.The average age(42.29±14.13)years old.There were 170 non-heavy patients and 70 severe patients.Clinical symptoms:The first symptoms were mainly fever(79.2%),cough(45.8%),and fatigue(12.5%).The average fever time after illness was(8.19±4.33)d.Comparison between the two groups:the number of white blood cells in the severe group(3.51±1.08)×10^(9)/L was significantly lower than that in the non-critical group(5.73±1.88)×10^(9)/L(P<0.05),and the number of lymphocytes in the severe group(0.70±0.16)×10^(9)/L compared with the non-severe group(3.51±1.08)×10^(9)/L(P<0.05),C-reactive protein(53.32±31.69)mg/L level in the severe group was higher than the non-severe group(16.97±21.46)mg/L significantly increased.The highest temperature between the two groups:the average maximum temperature of the severe group(38.6±0.42)℃was significantly higher than that of the non-severe group(37.9±0.59)℃.Chest CT:only 64.7%of patients in the non-severe group had multiple lobe involvement.In the severe group,100%of the patients had multiple lung involvement.There was no significant difference in fever days,fever days,and total disease duration between the two groups(P>0.05).Conclu

关 键 词：甲型H1N1流感 病毒性肺炎 临床特征 

分 类 号：R181.3[医药卫生—流行病学]