基于高脂血症探讨脾主运化的生理机制  

Study on the physiological mechanism of spleen governing transportation and transformation based on hyperlipidemia

作　　者：伍早霞 张启明[2] 王义国[2] WU Zaoxia;ZHANG Qiming;WANG Yiguo(Shaanxi University of Chinese Medicine,Shaanxi Province,Xianyang712046,China;Experimental Research Center,China Academy of Chinese Medical Sciences,Beijing100700,China)

机构地区：[1]陕西中医药大学,陕西咸阳712046 [2]中国中医科学院医学实验中心,北京100700

出　　处：《中国医药导报》2021年第25期128-131,共4页China Medical Herald

基　　金：国家重点研发计划项目(2019YFC1711705)。

摘　　要：高脂血症是由脂代谢紊乱引起的一种全身性疾病,属于中医学中“痰浊”“瘀血”等范畴,在其形成的整个过程中,脾主运化功能是否正常是其发病的关键。本文根据高脂血症的病因病机,以功能内涵为依据,从生理功能、解剖学定位、执行结构三个方面来探讨脾主运化的生理机制,从而发现脾主运化是水湿、精微物质运化的枢纽,是整个饮食物代谢过程的中心环节。脾主运化功能是由现代解剖学器官肝脏执行,其执行结构是具有消化、吸收、排泄功能的消化系统和具有新陈代谢功能的物质交换系统。Hyperlipidemia is a systemic disease caused by the disorder of lipid metabolism,it belongs to the category of“turbid phlegm”and“blood stasis”in traditional Chinese medicine.In the whole process of its formation,whether the function of spleen governing transportation and transformation is normal or not is the key to its pathogenesis.According to the etiology and pathogenesis of hyperlipidemia,and on the basis of functional connotation,this paper discusses the physiological mechanism of spleen governing transportation and transformation from three aspects:physiological function,anatomical location,and executive structure.Thus it is found that spleen governing transportation and transformation is the hinge of water-damp and fine matter transportation,and the central link of the whole diet metabolism process.The spleen’s function of governing transportation and transformation is performed by the modern anatomical organ liver.Its executive structure is the digestive system with digestion,absorption and excretion functions,and the material exchange system with metabolic function.

关 键 词：脾主运化 高脂血症 解剖学定位 执行结构 

分 类 号：R589.2[医药卫生—内分泌]