中老年人膝骨关节炎的影响因素分析  

Analysis of influential factors of knee osteoarthritis in middle-aged and old people

作　　者：王声雨[1] 林源[1] 陶树清[1] WANG Shengyu;LIN Yuan;TAO Shuqing(Department of Orthopedics,the Second Affiliated Hospital of Harbin Medical University,Heilongjiang Province,Harbin150086,China)

机构地区：[1]哈尔滨医科大学附属第二医院骨外科,黑龙江哈尔滨150086

出　　处：《中国医药导报》2021年第27期80-83,共4页China Medical Herald

基　　金：黑龙江省省属高等学校基本科研业务费科研项目(2018-KYYWF-0509);黑龙江省卫生计生委科研课题(2016-077)。

摘　　要：目的分析中老年人群原发性膝骨关节炎的相关危险因素。方法采用病例对照的研究方法,参考由中华医学会骨科分会制订的《骨关节炎诊治指南》(2007版)中膝关节骨性关节炎的诊断标准。选取哈尔滨医科大学附属第二医院关节外科于2016年1月至2017年1月收治的拟行膝关节置换手术的膝关节骨性关节炎患者76例和对照组患者71例作为研究对象,对相关影响因素筛选采用二分类logistic回归分析,包括单因素分析、多因素逐步筛选stepwise等。结果logistic回归分析发现,年龄(OR=1.074,95%CI:1.034~1.115,P<0.001)、使用铝制品炊具(OR=7.132,95%CI:1.508~33.718,P=0.013)、使用不锈钢制品炊具(OR=2.163,95%CI:1.010~4.631,P=0.047)是患膝关节骨性关节炎的危险因素。结论膝关节骨性关节炎的发病受年龄及是否使用铝制品和不锈钢制品炊影响。因此,可针对以上影响因素采取相应干预措施以预防膝关节骨性关节炎的发生。Objective To analyze the risk factors of primary knee osteoarthritis in middle-aged and elderly population.Methods A case-control study was conducted with reference to the diagnostic criteria of knee osteoarthritis in the Guidelines for the Diagnosis and Treatment of Osteoarthritis(2007 edition)formulated by the Orthopaedic Society of Chinese Medical Association.Seventy-six patients with knee osteoarthritis who were admitted to the Department of Joint Surgery of the Second Affiliated Hospital of Harbin Medical University from January 2016 to January 2017 and 71 patients in the control group were selected as the research objects.The relevant influencing factors were screened by binary logistic regression analysis.Including single factor analysis,multi-factor stepwise screening and so on.Results Logistic regression analysis showed that age(OR=1.074,95%CI:1.034-1.115,P<0.001),use of aluminum cooking utensils(OR=7.132,95%CI:1.508-33.718,P=0.013)and stainless steel cooking utensils(OR=2.163,95%CI:1.010-4.631,P=0.047)were risk factors for knee osteoarthritis.Conclusion The incidence of knee osteoarthritis is affected by age and the use of aluminum and stainless steel cooking utensils.Therefore,according to the above influencing factors,corresponding intervention measures can be taken to prevent the occurrence of knee osteoarthritis.

关 键 词：骨性关节炎 危险因素 膝关节 病例对照 

分 类 号：R446[医药卫生—诊断学]