超声心动图联合组织多普勒成像技术对孕晚期妊娠糖尿病伴妊娠期高血压疾病患者左心功能评价的研究  

Echocardiography combined with tissue Doppler imaging in the evaluation of left ventricular function in gestational diabetic patients with gestational hypertension in the third trimester of pregnancy

作　　者：毛玲玲 戴丽雅 吕晴 陈方红[1] MAO Lingling;DAI Liya;LYU Qing;CHEN Fanghong(Department of Ultrasound,Lishui Central Hospital,Lishui 323000,China)

机构地区：[1]丽水市中心医院超声科,323000

出　　处：《心电与循环》2021年第5期509-512,共4页Journal of Electrocardiology and Circulation

摘　　要：目的探讨超声心动图联合组织多普勒成像技术(TDI)对孕晚期妊娠糖尿病(GDM)伴妊娠期高血压疾病(HDCP)患者左心功能的评估价值。方法选择2019年5月至2020年5月在丽水市中心医院确诊的孕晚期GDM孕妇57例,根据其是否伴HDCP分成两组,GDM组31例,GDM+HDCP组26例,另选择同期在本院产检的孕晚期健康孕妇30例作为正常对照组,3组均行超声心动图检查获取:左心房前后径(LAD)、室间隔厚度(IVSd)、左心室后壁厚度(LVPWd)、左心室舒张末期内径(LVEDd)、左心室收缩末期内径(LVESd)、左心室射血分数(LVEF)、二尖瓣舒张早期速度峰值(E)及舒张晚期速度峰值(A),E/A值;进入TDI模式,获取室间隔e′、侧壁e′、室间隔E/e′、侧壁E/e′及平均E/e′,比较各组上述参数间的差异。结果3组对象LAD、室间隔e′、侧壁e′、室间隔E/e′、侧壁E/e′、平均E/e′比较,差异均有统计学意义(均P<0.05)。GDM+HDCP组LAD、室间隔E/e′、侧壁E/e′、平均E/e′高于正常对照组,室间隔e′、侧壁e′低于正常对照组,差异均有统计学意义(均P<0.05)。GDM组侧壁E/e′、平均E/e′高于正常对照组,侧壁e′低于正常对照组,差异均有统计学意义(均P<0.05)。GDM+HDCP组室间隔E/e′、侧壁E/e′、平均E/e′均高于GDM组,室间隔e′、侧壁e′均低于GDM组,差异均有统计学意义(均P<0.05)。结论GDM会引起孕妇左心室舒张功能减低,若伴HDCP则会加重舒张功能的损害。超声心动图联合TDI可早期评估孕晚期GDM的左心舒张功能。Objective To study the left ventricular function of pregnant women with gestational diabetes mellitus(GDM)and hypertensive disorder complicating pregnancy(HDCP)in the third trimester by echocardiography combined with tissue Doppler imaging(TDI).Methods Fifty-seven pregnant women with GDM diagnosed in Lishui Central Hospital from May 2019 to May 2020 were selected.According to whether they were accompanied by HDCP,they were divided into two groups:thirty-one cases in GDM group and twenty-six cases in GDM+HDCP group.In addition,thirty healthy pregnant women in the third trimester were selected as control group.Echocardiography was performed for all 3 groups:Left atrial diameter(LAD),interventricular septum thickness in diastole(IVSd),left ventricular posterior wall thickness at end-diastole(LVPWd),left ventricular end-diastolic diameter(LVEDd),left ventricular end-systolic diameter(LVESd),left ventricular ejection fraction(LVEF),mitral valve early diastolic velocity peak(E peak)and late diastolic velocity peak(A peak),E/A value;For TDI mode,interventricular septum e′,lateral wall e′,ventricular septum E/e′,lateral wall E/e′and average E/e′were obtained.The differences of above parameters in each group were compared and analyzed.Results There were statistically significant differences in LAD,interventricular septum e′,lateral wall e′,interventricular septum E/e′,lateral wall E/e′and average E/e′among the 3 groups(all P<0.05).LAD,ventricular septal E/e′,lateral wall E/e′and average E/e′in GDM+HDCP group were significantly higher than those in control group,while interventricular septal e′and lateral wall e′were significantly lower than those in control group(all P<0.05).The lateral wall E/e′and average E/e′of the GDM group were significantly higher than those of control group,and the lateral wall e′was significantly lower than that of control group(all P<0.05).The interventricular septal E/e′,lateral wall E/e′and average E/e′in GDM+HDCP group were significant higher than thos

关 键 词：妊娠糖尿病 妊娠期高血压疾病 超声心动图 组织多普勒成像技术 左心功能 

分 类 号：R714.256[医药卫生—妇产科学] R714.246[医药卫生—临床医学]