内分泌干扰物对鱼类性腺干扰的分子作用机制  

Molecular Mechanism of Endocrine Disruptors Interfering with Fish Gonads

作　　者：杨超超 潘鹏涛 谭婷 杨娜 雷忻[1,2] YANG Chaochao;PAN Pengtao;TAN Ting;YANG Na;LEI Xin(School of Life Sciences,Yan’an University;Research Center for Regional Resources Conservation and Utilization Engineering Technology,Yan’an 716000,China)

机构地区：[1]延安大学生命科学学院 [2]延安市生态恢复重点实验室,陕西延安716000

出　　处：《延安大学学报（自然科学版）》2021年第3期27-32,共6页Journal of Yan'an University：Natural Science Edition

基　　金：陕西省自然科学基础研究计划项目(2021JM-417);延安市科技惠民计划项目(2017HM-05);陕西省大学生创新创业训练计划项目(S201910719037)。

摘　　要：内分泌干扰物是严重危害生物及环境的化学污染物,探究其对生物的毒性作用是对其进行风险评价的基础。为深入了解其具体分子作用机制,对鱼类卵黄蛋白原、性类固醇激素、性腺发育相关基因干扰作用及其导致的性逆转等方面的研究成果与进展进行综述,并对目前研究中存在的问题以及有待深入研究的方面进行展望,旨在为鱼类毒理学研究以及水环境污染的治理提供参考。Endocrine disruptors are a class of environmental hormones that interfere with the endocrine system of creatures,widely distributed in the atmosphere,soil,water and other environments.Probing their foxic effects is the basis for the risk assessment.Through exploring the molecular mechanism of endocrine disruptors’action,summarizing research results and progress on their interference with fish vitellogenin,sex steroids,gonad development and sex reversal,and discussing existing problems in current research and aspects that need further study,reference was provided for fish toxicology research and relevant water pollution treatment.

关 键 词：内分泌干扰物 鱼类 性腺 基因 

分 类 号：Q955[生物学—动物学]