估算的脉搏波传导速度与臂踝脉搏波传导速度的分布及一致性分析  

The distribution and consistency of estimated pulse wave velocity and brachial-ankle pulse wave velocity

作　　者：季春鹏[1] 汪国栋 王娜[3] 刘妍[1] 王锦梅[4] 陈朔华 吴寿岭[1] JI Chunpeng;WANG Guodong;WANG Na;LIU Yan;WANG Jinmei;CHEN Shuohua;WU Shouling(Department of Cardiology,Kailuan General Hospital,Tangshan,Hebei 063000,China;Health Care Center,Kailuan Medical Group,Tangshan,Hebei 063000,China;Department of Cardiology,The Second Hospital of Qinhuangdao City,Qinhuangdao,Hebei 066600,China;General Internal Medicine,Rehabilitation Hospital,Kailuan General Hospital,Tangshan,Hebei 063000,China)

机构地区：[1]开滦总医院心内科,河北省唐山市063000 [2]开滦员工健康保障中心,河北省唐山市063000 [3]秦皇岛市第二医院心内科,河北省秦皇岛市066600 [4]开滦总医院康复医院普通内科,河北省唐山市063000

出　　处：《中国动脉硬化杂志》2021年第10期884-890,共7页Chinese Journal of Arteriosclerosis

基　　金：河北省卫健委青年科技课题(20210746)。

摘　　要：目的观察估算的脉搏波传导速度(ePWV)和臂踝脉搏波传导速度(baPWV)在开滦研究人群中的分布特征并分析二者的一致性(差异及关联)。方法选择参加baPWV检测且基线资料完整的43235例开滦集团公司职工作为观察人群。将研究对象按有无传统心血管危险因素分为风险人群和正常人群。在两人群中分别采用多元线性回归建立baPWV与年龄、年龄的平方、平均动脉压(MAP)的回归方程,并以此分别计算两人群的ePWV。观察ePWV和baPWV在人群中的分布特征并采用配对样本t检验和线性回归分析二者的差异和关联。结果在正常人群中,ePWV与baPWV分别为11.38±0.70 m/s和12.90±1.17 m/s;在风险人群中,ePWV与baPWV分别为14.29±1.85 m/s和15.74±1.76 m/s。无论在正常人群还是风险人群中,ePWV与baPWV均随年龄的增加而增加,男性的ePWV与baPWV均高于女性。同时,baPWV略高于ePWV(P<0.01),在正常人群和风险人群中,二者平均差值分别为1.80 m/s和2.17 m/s。线性回归分析结果提示,二者在总人群、正常人群和风险人群中的线性R2分别为0.428、0.279和0.388。结论ePWV与baPWV具有相似的年龄、性别分布特征。二者差值相对较小且具有良好的线性关联。因此,ePWV可作为baPWV的良好替代指标。Aim To observe the distribution and consistency of estimated pulse wave velocity(ePWV)and brachial-ankle pulse wave velocity(baPWV)in the Kailuan study population.Methods A total of 43235 employees with complete baseline data participated in the baPWV test.The participants were divided into the risk population and normal population according to the presence or absence of conventional cardiovascular risk factors.Multivariate linear regression was used to establish the regression equations between baPWV and quadratic age and mean arterial pressure in the two populations.The ePWV in the two populations was calculated according to the equations.The distribution of ePWV and baPWV was observed.The relationship between ePWV and baPWV was analyzed by paired sample t-test and linear regression.Results In the normal population,ePWV and baPWV were 11.38±0.70 m/s and 12.90±1.17 m/s,respectively.In the risk population,ePWV and baPWV were 14.29±1.85 m/s and 15.74±1.76 m/s,respectively.In the both of two populations,ePWV and baPWV increased with age,higher in men than those in women.ePWV was slightly lower than baPWV(P<0.001).The results of linear regression analysis indicated that ePWV and baPWV had a good linear correlation in the total population,normal population and risk population,and the linear R2 was 0.428,0.279 and 0.388,respectively.Conclusions ePWV and baPWV had a similar age and sex distribution.The difference was relatively small and a good linear correlation was found between ePWV and baPWV.Therefore,ePWV can be a good substitute for baPWV.

关 键 词：估算的脉搏波传导速度 臂踝脉搏波传导速度 分布特征 一致性 

分 类 号：R5[医药卫生—内科学]