硕通镜和经皮肾镜分别联合输尿管软镜治疗复杂性肾结石的效果  

Curative Effect of Negative Pressure Combined Ureteroscopy and Percutaneous Nephrolithotomy Respectively Combined with Flexible Ureteroscopy on Complex Renal Calculi

作　　者：林金松 LIN Jinsong(Longyan People’s Hospital,Longyan 364000,China)

机构地区：[1]龙岩人民医院,福建龙岩364000

出　　处：《中外医学研究》2021年第25期47-50,共4页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探究硕通镜(负压组合式输尿管镜)和经皮肾镜分别联合输尿管软镜治疗复杂性肾结石的效果。方法:选取本院2019年2月-2020年12月接收的复杂性肾结石患者60例,采用随机数表法简单随机分为观察组(n=30)和对照组(n=30)。给予对照组患者经皮肾镜联合输尿管软镜治疗,给予观察组患者硕通镜联合输尿管软镜治疗。比较两组患者手术治疗相关指标、血清C反应蛋白(CRP)、降钙素原(PCT)、肾功能相关指标及结石清除率与并发症发生率。结果:观察组手术时间、术中出血量、住院时间均明显优于对照组(P<0.05);治疗后,两组患者CRP、PCT水平均明显低于治疗前,且观察组治疗后CRP、PCT水平明显低于对照组(P<0.05);治疗后两组患者BUN、Scr、β_(2)-MG、BUA水平与治疗前相比均明显下降(P<0.05),观察组和对照组治疗后BUN、Scr、β_(2)-MG、BUA水平比较差异无统计学意义(P>0.05);治疗后观察组患者并发症发生率为6.67%,对照组并发症发生率为30.00%,观察组明显低于对照组(P<0.05);治疗后观察组结石清除率为100%,对照组结石清除率为80.00%,观察组明显高于对照组(P<0.05)。结论:与经皮肾镜联合输尿管软镜治疗相比,硕通镜联合输尿管软镜治疗复杂性肾结石可加快患者恢复,降低PCT、CRP水平,减少术后并发症。Objective:To explore the curative effect of negative pressure combined ureteroscopy and percutaneous nephrolithotomy respectively combined with flexible ureteroscopy on complex renal calculi and their influence on procalcitonin (PCT) level.Method:A total of 60 patients with complex renal calculi admitted to the hospital were enrolled from February 2019 and December 2020.They were divided into the observation group (n=30) and the control group (n=30) by random number table method.The control group underwent percutaneous nephrolithotomy combined with flexible ureteroscopy,while observation group underwent negative pressure combined ureteroscopycombined with flexible ureteroscopy.The surgical related indexes,serum C-reactive protein (CRP),PCT,renal function related indexes,stone clearance rate and incidence of complications were compared between the two groups.Result:The operation time,intraoperative blood loss and hospitalization time in observation group were significantly better than those in control group (P<0.05).After treatment,levels of CRP and PCT in both groups were significantly decreased,which were significantly lower in observation group than control group (P<0.05).After treatment,levels of BUN,Scr,β_(2)-MG and BUA in both groups were significantly decreased (P<0.05),but the differences of BUN,Scr,β_(2)-MG,BUA between the two groups were not statistically significant (P>0.05).After treatment,incidence of complications in observation group was significantly lower than that in control group (6.67% vs 30.00%) (P<0.05),and stone clearance rate was significantly higher than that in control group (100% vs 80.00%) (P<0.05).Conclusion:Compared with percutaneous nephrolithotomy combined with flexible ureteroscopy,negative pressure combined ureteroscopy combined with flexible ureteroscopy can accelerate the recovery of patients with complex renal calculi,decrease PCT and CRP levels,and reduce postoperative complications.

关 键 词：复杂性肾结石 输尿管软镜 负压组合式输尿管肾镜 经皮肾镜 降钙素原 

分 类 号：R699.2[医药卫生—泌尿科学]