一氧化碳参与不饱和烃类化合物羰基化反应的研究进展  

Recent Advances on Hydrocarbonylation of Unsaturated Hydrocarbons by Involving Carbon Monoxide

作　　者：王鹏[1] 刘欢 杨妲 WANG Peng;LIU Huan;YANG Da(State Key Laboratory of Organometallic Chemistry,Shanghai Institute of Organic Chemistry,Chinese Academy of Sciences,Shanghai 200032,China;Department of Chemistry,College of Science,China University of Petroleum(East China),Qingdao 266580,China)

机构地区：[1]中国科学院上海有机化学研究所,金属有机化学国家重点实验室,上海200032 [2]中国石油大学(华东)理学院化学系,青岛266580

出　　处：《高等学校化学学报》2021年第10期3024-3039,共16页Chemical Journal of Chinese Universities

基　　金：国家自然科学基金(批准号:21901250);中国博士后科学基金(批准号:2019M651625)资助.

摘　　要：不饱和烃类化合物的羰基化反应是指在过渡金属催化剂存在条件下,将一氧化碳(CO)分子以羰基的形式插入到烯烃(或者炔烃)与不同的亲核试剂中,合成更高附加值化学品的转化过程.本文综合评述了羰基化反应合成高附加值化学品的重要性,介绍了几种不同类型的羰基化反应(氢甲酰化反应、氢酯化反应、氢酰胺化反应和氢羧基化反应)在发展新型催化剂体系及高效合成目标产物方面的研究进展,并对羰基化反应存在的问题及未来发展方向和趋势进行了展望.Carbonylation of unsaturated hydrocarbons refers to the insertion of carbon monoxide(CO)into ole‐fins(or alkynes)and different nucleophiles in the form of carbonyl group,which higher value-added chemicals are synthesized in the presence of transition metal catalysts.In this paper,the importance of carbonylation reaction in the synthesis of high value-added chemicals was briefly introduced:(1)the synthetic route was simple and the target products could be synthesized in one step with high yield;(2)the starting materials of carbonylation reaction were cheap and various,such as natural fossil oils,petrochemical and coal chemical products etc.(3)Because the raw materials were cheap and the products were more useful,the economic bene‐fit was considerable.Then the application of several different types of carbonylation reactions(hydrofor‐mylation,hydroesterification,aminocarbonylation,hydrocarboxylation)in the development of new catalyst systems and efficient synthesis of target products were introduced.A variety of high value-added products like aldehyde,ester,amide or carboxylic acid were synthesized with high regio/chemoselectivity.Finally,the existing problems of carbonylation reaction and the future development direction and trend were prospected:(1)the application of cheap metal catalysts in carbonylation reaction;(2)developing more carbonylative substitutes on the basis of existing carbon monoxide surrogates;(3)carbonylation of some special olefins(1,3-dienes)to synthesize target compounds with high efficiency and regio/chemoselectivity;(4)explore the mech‐anism of carbonylation reaction process etc.It is expected to achieve the goal of green,cheap and recyclable carbonylation to produce high value-added carbonylative chemicals with high efficiency and selectivity.

关 键 词：烯烃 炔烃 一氧化碳 羰基化反应 高附加值化学品 

分 类 号：O643.32[理学—物理化学]