Efficacy of acupuncture therapy for improving anorexia in tumor patients:a Meta-analysis  

作　　者：ZHAO Weipeng LI Jing ZHANG Yushuang LI He HUANG Jinchang BAI Jing LI Jianbo 

机构地区：[1]Department of Acupuncture,the Fourth Hospital of Hebei Medical University,Shijiazhuang 050000,China [2]Traditional Chinese Medicine Hospital of Shijiazhuang,Shijiazhuang 050000,China [3]Department of Acupuncture and Minimally Invasive Oncology,Beijing University of Chinese Medicine Third Affiliated Hospital,Beijing 100029,China

出　　处：《Journal of Traditional Chinese Medicine》2021年第4期507-514,共8页中医杂志（英文版）

基　　金：Supported by National Natural Science Foundation of China(No.82074545);Hebei Provincial Administration of Traditional Chinese Medicine Research Project on Traditional Chinese Medicine(No.2019132)。

摘　　要：OBJECTIVE:To use evidence-based medicine to systematically evaluate the effectiveness and safety of acupuncture therapy for improving anorexia in tumor patients.METHODS:We queried the China National Knowledge Infrastructure Database(CNKI),China Science and Technology Journal Database(VIP),Wanfang Data,Pub Med,Cochrane Library,and Embase databases to identify reports of randomized controlled trials(RCTs)that applied acupuncture therapy to improve anorexia in tumor patients,and used Rev Man 5.3 software to conduct a Meta-analysis of the effective rate,appetite score,Karnofsky Performance Status(KPS)score,Functional Assessment of Anorexia/Cachexia Therapy(FAACT)appetite scale,and body weight in each study.Subgroup analysis was conducted based on whether radiotherapy or chemotherapy were also administered.RESULTS:A total of 10 RCTs were included with a total of 648 patients,including 343 patients in the treatment group and 305 patients in the control group.The Meta-analysis results showed that the clinical efficacy,appetite score,KPS score,and FAACT score of the treatment group(which received acupuncture to improve appetite)were better than those of the control group,and the difference was statistically significant(P<0.05);however,there was no statistically significant difference in body weight between the treatment group and the control group(P>0.05).The results of the subgroup analysis showed that the effective rate and appetite score for patients with long-term and chronic loss of appetite who underwent acupuncture were better than those of the control group,and the difference was statistically significant(P<0.05).CONCLUSIONS:Acupuncture therapy has good efficacy and safety in the treatment of anorexia in tumor patients,and it also has good efficacy and safety for long-term and chronic loss of appetite.The reliability and stability of the above results need to be confirmed by high-quality RCTs with larger sample sizes.

关 键 词：ACUPUNCTURE ANOREXIA NEOPLASMS treatment outcome safety META-ANALYSIS 

分 类 号：R246.5[医药卫生—针灸推拿学]