养血宣透方联合中药药浴治疗寻常型银屑病(血燥证)临床疗效观察  

Clinical efficacy of Yangxue Xuantou Decoction combined with traditional Chinese medicine bath in the treatment of psoriasis vulgaris(blood-dryness syndrome)

作　　者：王英杰[1] 姜珠倩[1] 彭勇[1] 武宗琴 刘杰[1] 罗瑞静[1] 李淑[1] 朱飞飞 康睿 WANG Ying-jie;JIANG Zhu-qian;PENG Yong;WU Zong-qin;LIU Jie;LUO Rui-jing;LI Shu;ZHU Fei-fei;KANG Rui(Department of Dermatology,Jiading District Traditional Chinese Medicine Hospital of Shanghai,Shanghai 201800,CHINA)

机构地区：[1]上海市嘉定区中医医院皮肤科,上海201800

出　　处：《海南医学》2021年第19期2529-2532,共4页Hainan Medical Journal

基　　金：上海市嘉定区卫生和计划生育委员会中医药科研课题(编号:2017-KY-ZYY-11);上海市嘉定区医学重点专科建设项目(编号:JDYXZDZK-7);上海市卫生和计划生育委员会中医药科研基金课题(编号:2014LP044A)。

摘　　要：目的观察养血宣透方联合中药药浴在寻常型银屑病(血燥证)治疗中的应用效果。方法选取2018年8月至2019年12月在上海市嘉定区中医医院治疗的138例银屑病患者,采用简单抽样法分为中药组、药浴组及联合组,每组46例,分别给予养血宣透方治疗、中药药浴治疗及养血宣透方联合中药药浴治疗,均治疗4周。比较三组患者的临床疗效、治疗前后的银屑病皮损面积与严重程度指数(PASI)评分、中医证候评分及治疗期间的不良反应发生情况。结果经过4周治疗,联合组患者的总有效率为97.83%,明显高于中药组的84.78%和药浴组的82.61%,差异具有统计学意义(P<0.05);治疗4周后,三组患者的PASI评分、中医证候评分较治疗前均下降,联合组分别为(1.71±0.37)分、(3.74±0.99)分,明显低于中药组的(3.81±0.87)分、(5.26±1.21)分和药浴组的(3.37±0.83)分、(5.66±1.43)分,差异均具有统计学意义(P<0.05);进一步分析各中医证候,治疗4周后,联合组和中药组患者的口干积分分别为(1.07±0.33)分和(0.78±0.15)分,明显低于药浴组的(2.15±0.37)分,联合组和药浴组患者的鳞屑积分分别为(0.67±0.18)分和(1.07±0.22)分,明显低于中药组的(1.84±0.43)分,差异均具有统计学意义(P<0.05);而瘙痒症状三组患者间比较差异无统计学意义(P>0.05)。结论养血宣透方联合中药药浴能够显著改善寻常型银屑病(血燥证)患者的临床症状及体征,疗效较单一治疗方案更佳。Objective To observe the application effect of Yangxue Xuantou Decoction combined with traditional Chinese medicine bath in psoriasis vulgaris(blood-dryness syndrome).Methods A total of 138 patients with psoriasis vulgaris who were treated in Jiading District Traditional Chinese Medicine Hospital of Shanghai from August 2018 to December 2019 were selected and divided into Chinese medicine group,Chinese medicine bath group,and combined group by simple sampling method,with 46 patients in each group,which were treated with Yangxue Xuantou Decoction,traditional Chinese medicine bath,and Yangxue Xuantou Decoction combined with traditional Chinese medicine bath,respectively,for 4 weeks.The clinical efficacy,psoriasis lesion area,and severity index(PASI)score before and after treatment,TCM syndrome score,and incidence of adverse reactions during treatment were compared among the three groups.Results After 4 weeks of treatment,the total effective rate of the combined group was 97.83%,which was significantly higher than 84.78%of the Chinese medicine group and 82.61%of the Chinese medicated bath group,and the difference was statistically significant(P<0.05).After 4 weeks of treatment,the PASI score and TCM syndrome score of the three groups decreased compared with those before treatment;the scores in the combined group were(1.71±0.37)points and(3.74±0.99)points,which were significantly lower than(3.81±0.87)points and(5.26±1.21)points in the Chinese medicine group and(3.37±0.83)points and(5.66±1.43)points in the Chinese medicine bath group,and the differences were statistically significant(P<0.05).In terms of TCM syndromes,after 4 weeks of treatment,the dry mouth scores of the combined group and the Chinese medicine group were(1.07±0.33)points and(0.78±0.15)points,which were lower than(2.15±0.37)points of the Chinese medicine bath group,and the scales scores of the combined group and the Chinese medicine bath group were(0.67±0.18)points and(1.07±0.22)points,which were lower than(1.84±0.43)points of the Chinese m

关 键 词：银屑病 血燥证 汗法 养血宣透方 养血透邪法 中药药浴 疗效 

分 类 号：R758.63[医药卫生—皮肤病学与性病学]